Evidence map›Paper›PMID 31612074›Full record

ArticleOxidative medicine and cellular longevity2019

Salidroside Delays Cellular Senescence by Stimulating Mitochondrial Biogenesis Partly through a miR-22/SIRT-1 Pathway.

Gen-Xiang Mao, Xiao-Gang Xu, San-Ying Wang, Hui-Fen Li, Jing Zhang, Zhong-Shan Zhang, Hui-Li Su, Sha-Sha Chen, Wen-Min Xing, Ya-Zhen Wang and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.5field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 38 citations in OpenAlex.

  1. Effects ofNutrients · 2026
    Trial
  2. Article
  3. Review
  4. Review
  5. Review
  6. The EPMA journal · 2024
    Review
  7. Article
  8. Article
  9. A synergistic blend ofFood & nutrition research · 2023
    Article
  10. Article
  11. Effects of salidroside on exercise tolerance of mice under high altitude hypoxia environment.Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2022
    Article
  12. Article
  13. Emerging Role of Non-Coding RNAs in Senescence.Frontiers in cell and developmental biology · 2022
    Review
  14. Nutrition Interventions of Herbal Compounds on Cellular Senescence.Oxidative medicine and cellular longevity · 2022
    Review
  15. Article
  16. Review
  17. Article
  18. Mitochondrial biogenesis: An update.Journal of cellular and molecular medicine · 2020
    Review
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 3 institutions in 2 countries.

Gen-Xiang MaoZhejiang Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.ORCID https://orcid.org/0000-0001-7061-4479
Xiao-Gang XuZhejiang Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.
San-Ying WangZhejiang Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.
Hui-Fen LiDivision of Geriatric Medicine and Gerontology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.
Jing ZhangZhejiang Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.
Zhong-Shan ZhangDepartment of Pharmacology, Huzhou University, Huzhou 313000, China.ORCID https://orcid.org/0000-0003-4991-0016
Hui-Li SuZhejiang Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.
Sha-Sha ChenZhejiang Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.
Wen-Min XingZhejiang Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.
Ya-Zhen WangZhejiang Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.
Ji-Huan DaiZhejiang Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.
Guo-Fu WangZhejiang Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.ORCID https://orcid.org/0000-0002-1948-8646
Sean X LengDivision of Geriatric Medicine and Gerontology, Department of Medicine, Johns Hopkins University School of Medicine, Baltimore, MD 21224, USA.ORCID https://orcid.org/0000-0002-2690-8055
Jing YanZhejiang Provincial Key Lab of Geriatrics & Geriatrics Institute of Zhejiang Province, Department of Geriatrics, Zhejiang Hospital, Hangzhou 310013, China.ORCID https://orcid.org/0000-0003-2758-685X
Zhejiang Hospital · CNJohns Hopkins University · USHuzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Calorie restriction (CR) is a nongenetic intervention with a robust effect on delaying aging in mammals and other organisms. A mild stimulation on mitochondrial biogenesis induced by CR seems to be an important action mode for its benefits. Here, we reported that a component isolated from

Indexed as

Cellular SenescenceGlucosidesHumansMicroRNAsMitochondriaOrganelle BiogenesisPhenolsRhodiolaGlucosidesMicroRNAsMIRN22 microRNA, humanPhenolsrhodioloside

Identifiers

PMID31612074
PMCPMC6757293
OpenAlexW2991695312

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.