Evidence map›Paper›PMID 31612013›Full record

ReviewOncology letters2019

Cancer stem cells in esophageal squamous cell cancer.

Qian Wu, Zhe Wu, Cuiyu Bao, Wenjing Li, Hui He, Yanling Sun, Zimin Chen, Hao Zhang, Zhifeng Ning

Open access · diamondAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
1.0field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 20 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Cancer stem-like cells contribute to paclitaxel resistance in esophageal squamous cell carcinoma.International journal of clinical and experimental pathology · 2022
    Article
  13. Article
  14. Review
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Qian WuBasic Medical School, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Zhe WuBasic Medical School, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Cuiyu BaoNurse School, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Wenjing LiBasic Medical School, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Hui HeBasic Medical School, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Yanling SunBasic Medical School, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Zimin ChenBasic Medical School, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Hao ZhangBasic Medical School, Ji'nan University Medical School, Guangzhou, Guangdong 510632, P.R. China.
Zhifeng NingBasic Medical School, Hubei University of Science and Technology, Xianning, Hubei 437100, P.R. China.
Hubei University of Science and Technology · CNJinan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cancer stem cells (CSCs) are hypothesized to govern the origin, progression, drug resistance, recurrence and metastasis of human cancer. CSCs have been identified in nearly all types of human cancer, including esophageal squamous cell cancer (ESCC). Four major methods are typically used to isolate or enrich CSCs, including: i) fluorescence-activated cell sorting or magnetic-activated cell sorting using cell-specific surface markers; ii) stem cell markers, including aldehyde dehydrogenase 1 family member A1; iii) side population cell phenotype markers; and iv) microsphere culture methods. ESCC stem cells have been identified using a number of these methods. An increasing number of stem cell signatures and pathways have been identified, which have assisted in the clarification of molecular mechanisms that regulate the stemness of ESCC stem cells. Certain viruses, such as human papillomavirus and hepatitis B virus, are also considered to be important in the formation of CSCs, and there is a crosstalk between stemness and viruses-associated genes/pathways, which may suggest a potential therapeutic strategy for the eradication of CSCs. In the present review, findings are summarized along these lines of inquiry.

Indexed as

cancer stem cellesophageal squamous cell canceridentificationisolationsignaling pathway

Identifiers

PMID31612013
PMCPMC6781610
OpenAlexW2973762430

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.