Evidence map›Paper›PMID 31611989›Full record

ArticleOncology letters2019

Expression of CREPT is associated with poor prognosis of patients with renal cell carcinoma.

Huaqi Yin, Qingfei Cao, Haiyue Zhao, Shenheng Wang, Weinan Chen, Xiaowei Zhang, Zhijie Chang, Tao Xu, Xiongjun Ye

Open access · diamondAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Oncology letters, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 6 citations in OpenAlex.

  1. Review
  2. An Important Role for RPRD1B in the Heat Shock Response.Molecular and cellular biology · 2022
    Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 1 country.

Huaqi YinDepartment of Urology, Peking University People's Hospital, The Second Clinical Medical College of Peking University, Beijing 100044, P.R. China.
Qingfei CaoDepartment of Urology, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning 121001, P.R. China.
Haiyue ZhaoDepartment of Urology, Peking University People's Hospital, The Second Clinical Medical College of Peking University, Beijing 100044, P.R. China.
Shenheng WangDepartment of Urology, Peking University People's Hospital, The Second Clinical Medical College of Peking University, Beijing 100044, P.R. China.
Weinan ChenDepartment of Urology, Peking University People's Hospital, The Second Clinical Medical College of Peking University, Beijing 100044, P.R. China.
Xiaowei ZhangDepartment of Urology, Peking University People's Hospital, The Second Clinical Medical College of Peking University, Beijing 100044, P.R. China.
Zhijie ChangState Key Laboratory of Membrane Biology, School of Medicine, Tsinghua University, Beijing 100084, P.R. China.
Tao XuDepartment of Urology, Peking University People's Hospital, The Second Clinical Medical College of Peking University, Beijing 100044, P.R. China.
Xiongjun YeDepartment of Urology, Peking University People's Hospital, The Second Clinical Medical College of Peking University, Beijing 100044, P.R. China.
Peking University · CNPeking University People's Hospital · CNJinzhou Medical University · CNTsinghua University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cell-cycle-associated and expression-elevated protein in tumor (CREPT) functions as a cell cycle modulator that enhances the transcription of cyclin D1 by interacting with RNA polymerase II. CREPT has been identified to be overexpressed in various human cancer types; however, the expression and significance of CREPT in renal cell carcinoma (RCC) has remained largely elusive. In the present study, increased expression of CREPT was identified in 46.7% RCC tissues compared with adjacent normal tissue (31.1%; P=0.032) using immunohistochemistry. Furthermore, overexpression of CREPT was significantly associated with the Tumor-Node-Metastasis stage (χ

Indexed as

cell-cycle-related and expression-elevated protein in tumorc-myccyclin D1prognosisproliferationrenal cell carcinoma

Identifiers

PMID31611989
PMCPMC6781659
OpenAlexW2972774174

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.