Evidence map›Paper›PMID 31611772›Full record

ArticleFrontiers in molecular neuroscience2019

Developmental Expression of Mutant PFN1 in Motor Neurons Impacts Neuronal Growth and Motor Performance of Young and Adult Mice.

Merryn Brettle, Holly Stefen, Aleksandra Djordjevic, Sandra Y Y Fok, Josephine W Chan, Annika van Hummel, Julia van der Hoven, Magdalena Przybyla, Alexander Volkerling, Yazi D Ke and 3 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in molecular neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

  1. Review
  2. Article
  3. Modelling amyotrophic lateral sclerosis in rodents.Nature reviews. Neuroscience · 2022
    Review
  4. Review
  5. Review
  6. Profilin Isoforms in Health and Disease - All the Same but Different.Frontiers in cell and developmental biology · 2021
    Review
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 3 institutions in 1 country.

Merryn BrettleSchool of Medical Sciences, Faculty of Medicine, UNSW Sydney, Randwick, NSW, Australia.
Holly StefenDementia Research Centre and Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
Aleksandra DjordjevicSchool of Medical Sciences, Faculty of Medicine, UNSW Sydney, Randwick, NSW, Australia.
Sandra Y Y FokSchool of Medical Sciences, Faculty of Medicine, UNSW Sydney, Randwick, NSW, Australia.
Josephine W ChanSchool of Medical Sciences, Faculty of Medicine, UNSW Sydney, Randwick, NSW, Australia.
Annika van HummelDementia Research Centre and Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
Julia van der HovenDementia Research Centre and Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
Magdalena PrzybylaDementia Research Centre and Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
Alexander VolkerlingSchool of Medical Sciences, Faculty of Medicine, UNSW Sydney, Randwick, NSW, Australia.
Yazi D KeDementia Research Centre and Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
Fabien DelerueDementia Research Centre and Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
Lars M IttnerDementia Research Centre and Department of Biomedical Sciences, Faculty of Medicine and Health Sciences, Macquarie University, Sydney, NSW, Australia.
Thomas FathSchool of Medical Sciences, Faculty of Medicine, UNSW Sydney, Randwick, NSW, Australia.
Macquarie University · AUUNSW Sydney · AUNational Imaging Facility · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amyotrophic lateral sclerosis (ALS) is a devastating neurodegenerative disease with limited treatment and no cure. Mutations in

Indexed as

actinamyotrophic lateral sclerosismotor neuronsneurodegenerationprofilin 1

Identifiers

PMID31611772
PMCPMC6776973
OpenAlexW2973461347

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.