Evidence map›Paper›PMID 31611749›Full record

ArticleEXCLI journal2019

Cytoprotective effects of ginsenoside Rd on apoptosis-associated cell death in the isolated human pancreatic islets.

Maryam Kaviani, Somayeh Keshtkar, Negar Azarpira, Mahdokht Hossein Aghdaei, Bita Geramizadeh, Mohammad Hossein Karimi, Ramin Yaghobi, Elaheh Esfandiari, Alireza Shamsaeefar, Saman Nikeghbalian and 1 more

Open access · greenAbstract read
In one paragraph

Article in EXCLI journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Review
  2. Review
  3. Review
  4. Analysis of the Effects of Ninjin'yoeito on Physical Frailty in Mice.International journal of molecular sciences · 2022
    Article
  5. Review
  6. Review
  7. Article
  8. Article
  9. Effect ofFrontiers in pharmacology · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 2 countries.

Maryam KavianiTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Somayeh KeshtkarTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Negar AzarpiraTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mahdokht Hossein AghdaeiTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Bita GeramizadehTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Mohammad Hossein KarimiTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ramin YaghobiTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Elaheh EsfandiariTransplant Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Alireza ShamsaeefarShiraz Organ Transplant Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Saman NikeghbalianShiraz Organ Transplant Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Ismail H Al-AbdullahDepartment of Translational Research and Cellular Therapeutics, Diabetes and Metabolism Research Institute, Beckman Research Institute of City of Hope, Duarte, USA.
Shiraz University of Medical Sciences · IRBeckman Research Institute

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ginsenoside Rd (GS-Rd), one of the main pharmacologically active components of ginseng, has shown the potential to stabilize mitochondrial membrane integrity and decrease apoptotic death in neuronal and non-neuronal cells. The present study aimed to evaluate the effect of this bioactive molecule on the apoptosis-associated cell death in human pancreatic islets. In this regard human pancreatic islets were isolated and grouped for the treatment with GS-Rd. The isolated islets were treated with different concentrations of GS-Rd. After 24 and 72 h of incubation, the islets were evaluated in terms of viability,

Indexed as

apoptosiscultureGinsenoside Rdhuman pancreatic isletsinsulintransplantation

Identifiers

PMID31611749
PMCPMC6785759
OpenAlexW3021540927

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.