Evidence map›Paper›PMID 31611706›Full record

ArticleNature neuroscience2019

State-specific gating of salient cues by midbrain dopaminergic input to basal amygdala.

Andrew Lutas, Hakan Kucukdereli, Osama Alturkistani, Crista Carty, Arthur U Sugden, Kayla Fernando, Veronica Diaz, Vanessa Flores-Maldonado, Mark L Andermann

Abstract read
In one paragraph

Article in Nature neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 103 papers.

0numbers the graph read from it
0cells of the map it votes in
103citing papers in PubMed
8.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

103 citing papers in PubMed, 185 citations in OpenAlex.

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  16. A lateralized pathway for associating nutrients with flavors.bioRxiv : the preprint server for biology · 2025
    Article
  17. Article
  18. Article
  19. A hardwired neural circuit for temporal difference learning.bioRxiv : the preprint server for biology · 2025
    Article
  20. Article

43 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Andrew LutasDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.ORCID http://orcid.org/0000-0002-6991-2898
Hakan KucukdereliDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Osama AlturkistaniDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Crista CartyDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Arthur U SugdenDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Kayla FernandoDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Veronica DiazDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Vanessa Flores-MaldonadoDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA.
Mark L AndermannDivision of Endocrinology, Metabolism, and Diabetes, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA, USA. manderma@bidmc.harvard.edu.ORCID http://orcid.org/0000-0002-9882-933X
Beth Israel Deaconess Medical Center · US

Funding

Transgenic CoreP30DK046200 · NIDDK · TUFTS MEDICAL CENTER · PI GREENBERG, ANDREW S, PERISSI, VALENTINA · 1992 to 2021
$25.0M
INTEGRATED ENDOCRINE &METABOLIC RESEARCH TRAININGT32DK007516 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI BARBARA B. KAHN · 1986 to 2026
$6.8M
FUNDAMENTAL NEUROBIOLOGYT32NS007484 · NINDS · HARVARD UNIVERSITY (MEDICAL SCHOOL) · PI REGEHR, WADE G · 2000 to 2014
$5.9M
Multiphoton Imaging of Thoughts of Food During Natural and Induced Hunger StatesDP2DK105570 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ANDERMANN, MARK L · 2014 to 2014
$2.5M
Neural Pathway Linking Nutritional State To Food-Cue Responses In Insular CortexR01DK109930 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI ANDERMANN, MARK L · 2016 to 2020
$2.2M
Hunger modulation of food cue responses in amygdala by dopamine and ghrelinF32DK112589 · NIDDK · BETH ISRAEL DEACONESS MEDICAL CENTER · PI LUTAS, ANDREW · 2017 to 2019
$121k
NIDDK NIH HHS DP2 DK105570NIDDK NIH HHS F32 DK112589NIDDK NIH HHS P30 DK046200NIDDK NIH HHS R01 DK109930NIDDK NIH HHS T32 DK007516NINDS NIH HHS T32 NS007484
6 · The paper itself

Abstract

Basal amygdala (BA) neurons guide associative learning via acquisition of responses to stimuli that predict salient appetitive or aversive outcomes. We examined the learning- and state-dependent dynamics of BA neurons and ventral tegmental area (VTA) dopamine (DA) axons that innervate BA (VTA

Indexed as

AmygdalaAnimalsCalcium-Calmodulin-Dependent Protein Kinase Type 2CuesDopamine Plasma Membrane Transport ProteinsDopaminergic NeuronsFemaleMaleMiceMice, TransgenicNeural PathwaysPhotic StimulationPunishmentRewardSensory GatingVentral Tegmental AreaCalcium-Calmodulin-Dependent Protein Kinase Type 2Dopamine Plasma Membrane Transport ProteinsSlc6a3 protein, mouse

Identifiers

PMID31611706
PMCPMC6858554
OpenAlexW2979655670

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.