ArticleNature chemistry2019
An enzymatic platform for the asymmetric amination of primary, secondary and tertiary C(sp
Article in Nature chemistry, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 62 papers.
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Who cites it
62 citing papers in PubMed.
- Stereoselective Synthesis of Aminals Through Enzyme-Catalyzed Intermolecular C(spAngewandte Chemie (International ed. in English) · 2026Article
- Design-Evolution Synergy Enables New-to-Nature Enzyme Chemistry.bioRxiv : the preprint server for biology · 2026Article
- Photoinduced cobalt-catalyzed enantioconvergent synthesis of 1,3-diamines via aziridine ring-opening addition.Science advances · 2026Article
- Reaction Pathway and Axial Ligand Effects of C(spJACS Au · 2026Article
- A biocatalytic platform for the stereoselective synthesis of diverse atropisomeric compounds using engineered metalloenzymes.Science advances · 2026Article
- Highly stereoselective synthesis of allylic β-lactamsChemical science · 2026Article
- Engineering Enantiocomplementary Protoglobins for Stereoconvergent Construction ofJournal of the American Chemical Society · 2026Article
- Nonheme Fe Enzyme-Catalyzed Enantiodivergent Nitrogen Migration: Directed Evolution and Computational Study of Isopenicillin N Synthases for Biocatalytic Synthesis of Arylglycines.Angewandte Chemie (International ed. in English) · 2026Article
- Stereoselective cyano translocation reaction enabled by photoenzymatic catalysis.Nature communications · 2026Article
- Ligand-controlled regiodivergent and enantioselective C-H cyanation of secondary amines.Nature communications · 2026Article
- Protein engineering: status report.Protein engineering, design & selection : PEDS · 2026Review
- Nonheme Fe 1,3-nitrogen migratases for asymmetric noncanonical amino acid synthesis.Nature chemical biology · 2025Article
- Porphyrins as cofactors in enzyme-catalyzed organic reactions.Biophysics reports · 2025Article
- Bimolecular Homolytic Substitution (SACS central science · 2025Review
- Highly Enantioselective Construction of Oxazolidinone Rings via Enzymatic C(spACS catalysis · 2025Article
- Radical-Mediated Regiodivergent C(Chem catalysis · 2024Article
- Iron Corrole-Catalyzed Intramolecular Amination Reactions of Alkyl Azides. Spectroscopic Characterization and Reactivity of [FeAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024Article
- Recent Progress on Peroxidase Modification and Application.Applied biochemistry and biotechnology · 2024Review
- Biocatalytic, Enantioenriched Primary Amination of Tertiary C-H Bonds.Nature catalysis · 2024Article
- Article
2 more citing papers are in PubMed but not listed here.
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Authors and funding
5 authors.
Funding
Abstract
The ability to selectively functionalize ubiquitous C-H bonds streamlines the construction of complex molecular architectures from easily available precursors. Here we report enzyme catalysts derived from a cytochrome P450 that use a nitrene transfer mechanism for the enantioselective amination of primary, secondary and tertiary C(sp
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