Evidence map›Paper›PMID 31611617›Full record

ArticleJournal of perinatology : official journal of the California Perinatal Association2020

Postmenstrual age at discharge in premature infants with and without ventilatory pattern instability.

Jeffery Hoover, Jennifer Wambach, Akshaya Vachharajani, Barbara Warner, John L Carroll, James S Kemp

Open access · greenAbstract read
In one paragraph

Article in Journal of perinatology : official journal of the California Perinatal Association, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 41% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 4 citations in OpenAlex.

  1. Tracheostomy Tube Change Versus PEEP Titration on Tracheostomy-Dependent Infants With Airway Malacia and Ventilator Instability.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Jeffery HooverDivision of Newborn Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA. jeffhoover5@gmail.com.
Jennifer WambachDivision of Newborn Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Akshaya VachharajaniDivision of Neonatology, University of Missouri in Columbia, Columbia, MO, 65211, USA.
Barbara WarnerDivision of Newborn Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA.
John L CarrollDivision of Pulmonary and Sleep Medicine, University of Arkansas for Medical Sciences, Fayetteville, AR, 72701, USA.
James S KempDivision of Allergy, Immunology, and Pulmonary Medicine, Washington University School of Medicine, St. Louis, MO, 63110, USA.
Washington University in St. Louis · USUniversity of Arkansas for Medical Sciences · USUniversity of Missouri · US

Funding

PHYSIOLOGIC BIOMARKERS PREDICTING VENTILATORY INSTABILITY AND HYPOXEMIA IN PREMATURE INFANTSU01HL133700 · NHLBI · WASHINGTON UNIVERSITY · PI CARROLL, JOHN L, KEMP, JAMES SCOTT · 2016 to 2020
$2.4M
NHLBI NIH HHS U01 HL133700
6 · The paper itself

Abstract

rationaleTo determine if ventilatory pattern instability, manifested as periodic breathing (PB) during physiologic challenge testing, affects postmenstrual age (PMA) at discharge.

methodsEighty infants underwent challenge testing at 36 weeks PMA. Infants breathing supplemental O

resultsThere were no clinical or demographic differences between groups. Infants who passed their challenge testing were, on average, discharged 1.6 weeks sooner than those who failed. The groups of ventilatory control phenotypes differed in PMA at discharge (p = 0.0020), but those with PB were younger by PMA at discharge.

conclusionsVentilatory pattern instability did not prolong time to discharge. Passing either challenge was associated with earlier discharge, suggesting these tests might identify infants who can have nasal cannula support removed and be safely discharged sooner. Most of the infants who failed their challenge tests with PB were receiving nasal cannula support. Nasal cannula support may be not only treating hypoxemia due to bronchopulmonary dysplasia (BPD), but also mitigating their ventilatory pattern instability.

Indexed as

Infant, PrematureLength of StayPatient DischargeRespiration, ArtificialAge FactorsBronchopulmonary DysplasiaChronic DiseaseFemaleHumansHypoxiaInfant, NewbornInfant, Premature, DiseasesLung DiseasesMale

Identifiers

PMID31611617
PMCPMC7480785
OpenAlexW2979320392

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.