Evidence map›Paper›PMID 31611608›Full record

ArticleScientific reports2019

Endogenous intronic antisense long non-coding RNA, MGAT3-AS1, and kidney transplantation.

Subagini Nagarajah, Shengqiang Xia, Marianne Rasmussen, Martin Tepel

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.3field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 11 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 3 institutions in 2 countries.

Subagini NagarajahOdense University Hospital, Department of Nephrology, Odense, Denmark.
Shengqiang XiaDepartment of Urology, Renji Hospital, School of Medicine, Shanghai Jiaotong University, Shanghai, P.R. China.
Marianne RasmussenOdense University Hospital, Department of Nephrology, Odense, Denmark.
Martin TepelOdense University Hospital, Department of Nephrology, Odense, Denmark. mtepel@health.sdu.dk.
University of Southern Denmark · DKOdense University Hospital · DKRenji Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

β-1,4-mannosylglycoprotein 4-β-N-acetylglucosaminyltransferase (MGAT3) is a key molecule for the innate immune system. We tested the hypothesis that intronic antisense long non-coding RNA, MGAT3-AS1, can predict delayed allograft function after kidney transplantation. We prospectively assessed kidney function and MGAT3-AS1 in 129 incident deceased donor kidney transplant recipients before and after transplantation. MGAT3-AS1 levels were measured in mononuclear cells using qRT-PCR. Delayed graft function was defined by at least one dialysis session within 7 days of transplantation. Delayed graft function occurred in 22 out of 129 transplant recipients (17%). Median MGAT3-AS1 after transplantation was significantly lower in patients with delayed graft function compared to patients with immediate graft function (6.5 × 10

Indexed as

Kidney TransplantationDelayed Graft FunctionGene ExpressionHumansKidneyLeukocytes, MononuclearMiddle AgedPrognosisProspective StudiesRenal DialysisRNA, Long NoncodingRNA, Long Noncoding

Identifiers

PMID31611608
PMCPMC6791892
OpenAlexW2979316227

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.