Evidence map›Paper›PMID 31611578›Full record

ArticleScientific reports2019

Dendritic cells and regulatory T cells expressing CCR4 provide resistance to coxsackievirus B5-induced pancreatitis.

Marcela C S Françozo, Frederico R C Costa, Isabel C Guerra-Gomes, João S Silva, Renata Sesti-Costa

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
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  8. CCL17-CCR4 axis contributes to the onset of vitiligo in mice.Immunity, inflammation and disease · 2021
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Marcela C S FrançozoInstitute of Pathology, Hannover Medical School, Hannover, Germany.ORCID http://orcid.org/0000-0001-8436-9830
Frederico R C CostaDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo - USP, Ribeirão Preto, São Paulo, Brazil.
Isabel C Guerra-GomesDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo - USP, Ribeirão Preto, São Paulo, Brazil.
João S SilvaDepartment of Biochemistry and Immunology, Ribeirão Preto Medical School, University of São Paulo - USP, Ribeirão Preto, São Paulo, Brazil. jsdsilva@fmrp.usp.br.
Renata Sesti-CostaHematology Center, University of Campinas - UNICAMP, Campinas, São Paulo, Brazil. resesti@unicamp.br.ORCID http://orcid.org/0000-0002-7098-2850
Universidade de São Paulo · BRMedizinische Hochschule Hannover · DEUniversidade de Ribeirão Preto · BRUniversidade Estadual de Campinas (UNICAMP) · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Type B coxsackieviruses (CVB) are enteroviruses responsible for a common infectious myocarditis and pancreatitis. DCs and regulatory T cells (Tregs) are key players in controlling virus replication and regulating the immune response and tissue damage, respectively. However, the mechanisms underlying cellular migration to target tissues remain unclear. In the present study, we found that CVB5 infection induced CCL17 production and controlled the migration of CCR4

Indexed as

AnimalsCell MovementChemokine CCL17Coxsackievirus InfectionsDendritic CellsEnterovirus B, HumanMice, Inbred C57BLPancreatitisReceptors, CCR4T-Lymphocytes, RegulatoryCcr4 protein, mouseChemokine CCL17Receptors, CCR4

Identifiers

PMID31611578
PMCPMC6791842
OpenAlexW2979883485

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.