ArticleProceedings of the National Academy of Sciences of the United States of America2019
Maternal prenatal stress phenotypes associate with fetal neurodevelopment and birth outcomes.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 101 papers, 3 of them syntheses that pooled it.
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Who cites it
101 citing papers in PubMed, 3 syntheses or guidelines pooled it, 263 citations in OpenAlex.
- Risks to the Unborn: An Umbrella Review on the Effects of Prenatal Maternal Stress Caused by Natural Disasters.Stress and health : journal of the International Society for the Investigation of Stress · 2025Pooled it
- Association between gestational hypnotic benzodiazepine receptor agonists exposure and adverse pregnancy outcomes: a systematic review and meta-analysis.Archives of women's mental health · 2025Pooled it
- Effects of mHealth on the psychosocial health of pregnant women and mothers: a systematic review.BMJ open · 2022Pooled it
- Effects of Two Group Prenatal Care Interventions on Mental Health: An RCT.American journal of preventive medicine · 2024Trial
- Maternal Social Support Reshapes the Offspring Brain Transcriptome to Buffer Prenatal Stress in Mice.Research square · 2026Article
- Intergenerational effects of the microbiota on neurodevelopment: mechanisms and therapeutic perspectives.Acta pharmacologica Sinica · 2026Review
- Understanding the Lived Experience of Fetal and Neonatal Alloimmune Thrombocytopenia: A Qualitative Study.AJP reports · 2026Article
- Factors associated with birth weight and birth length among term newborns in Vietnam: a retrospective cross-sectional study.Child health nursing research · 2026Article
- Healthy Prenatal Diet Associated with Lower Risk of Excessive Gestational Weight Gain in a Predominantly Latina Sample.Nutrients · 2026Article
- Prenatal Stress Induces Changes in Behavior, HPA Axis, Inflammation, and Oxidative Stress in Adult Rats Offspring.Neurochemical research · 2026Article
- Coping Styles, Postpartum Depression, and Anxiety in Romanian Women: A Cross-Sectional Study Using the Brief COPE Inventory.Journal of clinical medicine · 2026Article
- Expression of Glucocorticoid and Mineralocorticoid Receptors in the Offspring of Mothers Experiencing Chronic Stress during Pregnancy.Current topics in medicinal chemistry · 2026Article
- Perinatal and laboratory determinants of fortified human milk use: a case-control study.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologicas · 2026Article
- Levels of stress, anxiety, and depression during pregnancy after bariatric surgery: A comparative study with women with obesity.Journal of education and health promotion · 2026Article
- Hospital information system based psychological nursing improves maternal and neonatal outcomes in cesarean section patients.Scientific reports · 2025Article
- Effect of gestational diabetes on neurodevelopment outcome of the offsprings- Ma'an shan birth cohort study.BMC pediatrics · 2025Article
- Sex-selective abortion bans and the birth outcomes of Asian immigrants.Social science & medicine (1982) · 2025Article
- Neuroendocrine Regulation and Neural Circuitry of Parenthood: Integrating Neuropeptides, Brain Receptors, and Maternal Behavior.International journal of molecular sciences · 2025Review
- Maternal prenatal stress induces sex-dependent changes in tRNA fragment families and cholinergic pathways in newborns.Molecular psychiatry · 2025Article
- Development of Powerly, unguided mobile app intervention preventing postpartum depression and anxiety & study protocol of randomized clinical trial.Internet interventions · 2025Article
41 more citing papers are in PubMed but not listed here.
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13 authors at 5 institutions in 1 country.
Funding
Abstract
Maternal prenatal stress influences offspring neurodevelopment and birth outcomes including the ratio of males to females born; however, there is limited understanding of what types of stress matter, and for whom. Using a data-driven approach with 27 variables from questionnaires, ambulatory diaries, and physical assessments collected early in the singleton pregnancies of 187 women, 3 latent profiles of maternal prenatal stress emerged that were differentially associated with sex at birth, birth outcomes, and fetal neurodevelopment. Most women (66.8%) were in the healthy group (HG); 17.1% were in the psychologically stressed group (PSYG), evidencing clinically meaningful elevations in perceived stress, depression, and anxiety; and 16% were in the physically stressed group (PHSG) with relatively higher ambulatory blood pressure and increased caloric intake. The population normative male:female secondary sex ratio (105:100) was lower in the PSYG (2:3) and PHSG (4:9), and higher in the HG (23:18), consistent with research showing diminished male births in maternal stress contexts. PHSG versus HG infants were born 1.5 wk earlier (
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