ArticleProceedings of the National Academy of Sciences of the United States of America2019
Amazon deforestation drives malaria transmission, and malaria burden reduces forest clearing.
Article in Proceedings of the National Academy of Sciences of the United States of America, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 97 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
97 citing papers in PubMed, 3 syntheses or guidelines pooled it, 239 citations in OpenAlex.
- 2000-2025: A Quarter of a Century of Studies on Pet Ownership in the Amazon-Epidemiological Implications for Public Health.Pathogens (Basel, Switzerland) · 2026Pooled it
- A systematic review investigating emerging trends between Extreme Weather Events (EWEs) and infectious disease outbreaks in South Africa.Frontiers in public health · 2026Pooled it
- Malaria, relationship with climatic variables and deforestation in Colombia, Latin America and the Caribbean from 2000 to 2020: a systematic review.Malaria journal · 2024Pooled it
- Resurgence of Malaria in Protected and Rural Areas After Successful Control Program in a Brazilian Amazon Municipality.GeoHealth · 2026Article
- Associations between weather and Plasmodium vivax malaria in an Amazonian elimination setting: a distributed lag analysis from 2017 to 2024.Malaria journal · 2026Article
- Ecology of Malaria Mortality: A Spatiotemporal Mapping Approach.American journal of biological anthropology · 2026Article
- Synthetic control methods enable stronger causal inference using participatory science data in cities.Nature ecology & evolution · 2026Article
- Tree cover loss in the Americas: a critical indicator linking climate mitigation and planetary health.Lancet regional health. Americas · 2026Review
- Climate change and Plasmodium vivax Malaria Risk in Brazil: Developing adaptive tool for Brazilian Municipalities.PLoS neglected tropical diseases · 2026Article
- Oil palm expansion reshapes Culicoides assemblages and avian haemosporidian infections.Parasites & vectors · 2026Article
- MIReVTD, a minimum information standard for reporting vector trait data.GigaScience · 2026Article
- Investigating the Yanomami malaria outbreak: gold mining and malaria.Biology letters · 2026Article
- Ecologies of Risk: Malaria and Settler Landscape Transformation in 19th-Century Ontario.American journal of human biology : the official journal of the Human Biology Council · 2026Article
- Climate change and tropical medicine in the Amazon: contributions from a research center, gaps and future priorities.Revista da Sociedade Brasileira de Medicina Tropical · 2026Review
- Mining and malaria in the Brazilian Amazon and in the Yanomami indigenous land.PLoS neglected tropical diseases · 2025Article
- Extreme climate whiplash events drive divergent responses of mosquito-borne disease.PNAS nexus · 2025Article
- Connecting the dots: Managing species interaction networks to mitigate the impacts of global change.eLife · 2025Review
- Article
- Towards a 'people and nature' paradigm for biodiversity and infectious disease.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025Review
- Detection of endosymbiotic, environmental, and potential bacterial pathogens in diverse mosquito taxa from Colombian tropical forests using RNAseq.Frontiers in microbiology · 2025Article
37 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
- Erratum issued
Authors and funding
2 authors at 2 institutions in 1 country.
Funding
Abstract
Deforestation and land use change are among the most pressing anthropogenic environmental impacts. In Brazil, a resurgence of malaria in recent decades paralleled rapid deforestation and settlement in the Amazon basin, yet evidence of a deforestation-driven increase in malaria remains equivocal. We hypothesize an underlying cause of this ambiguity is that deforestation and malaria influence each other in bidirectional causal relationships-deforestation increases malaria through ecological mechanisms and malaria reduces deforestation through socioeconomic mechanisms-and that the strength of these relationships depends on the stage of land use transformation. We test these hypotheses with a large geospatial dataset encompassing 795 municipalities across 13 y (2003 to 2015) and show deforestation has a strong positive effect on malaria incidence. Our results suggest a 10% increase in deforestation leads to a 3.3% increase in malaria incidence (∼9,980 additional cases associated with 1,567 additional km
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.