Evidence map›Paper›PMID 31611303›Full record

ArticleOccupational and environmental medicine2019

Workload and cross-harvest kidney injury in a Nicaraguan sugarcane worker cohort.

Erik Hansson, Jason Glaser, Ilana Weiss, Ulf Ekström, Jenny Apelqvist, Christer Hogstedt, Sandra Peraza, Rebekah Lucas, Kristina Jakobsson, Catharina Wesseling and 1 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Occupational and environmental medicine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 60 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
60citing papers in PubMed, 2 pooled it
4.6field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

60 citing papers in PubMed, 2 syntheses or guidelines pooled it, 97 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Work and work exposures in sugarcane farming in Eswatini, Southern Africa.International archives of occupational and environmental health · 2025
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Heat-induced kidney disease: Understanding the impact.Journal of internal medicine · 2025
    Review
  18. Article
  19. Scoping Review of Climate Change Adaptation Interventions for Health: Implications for Policy and Practice.International journal of environmental research and public health · 2024
    Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 7 institutions in 5 countries.

Erik HanssonLa Isla Network, Washington, District of Columbia, USA.ORCID 0000-0002-9779-6820
Jason GlaserLa Isla Network, Washington, District of Columbia, USA jason@laislanetwork.org.
Ilana WeissLa Isla Network, Washington, District of Columbia, USA.
Ulf EkströmLa Isla Network, Washington, District of Columbia, USA.
Jenny ApelqvistLa Isla Network, Washington, District of Columbia, USA.
Christer HogstedtLa Isla Network, Washington, District of Columbia, USA.
Sandra PerazaLa Isla Network, Washington, District of Columbia, USA.
Rebekah LucasLa Isla Network, Washington, District of Columbia, USA.
Kristina JakobssonLa Isla Network, Washington, District of Columbia, USA.
Catharina WesselingLa Isla Network, Washington, District of Columbia, USA.
David H WegmanLa Isla Network, Washington, District of Columbia, USA.
Action Network · USKarolinska Institutet · SELund University · SECenter for Health, Exercise and Sport Sciences · RSRealNetworks (United States) · USSahlgrenska University Hospital · SEUniversity of Massachusetts Lowell · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo examine the association between workload and kidney injury in a fieldworker cohort with different levels of physically demanding work over a sugarcane harvest, and to assess whether the existing heat prevention efforts at a leading occupational safety and health programme are sufficient to mitigate kidney injury.

methodsBiological and questionnaire data were collected before (n=545) and at the end (n=427) of harvest among field support staff (low workload), drip irrigation workers (moderate), seed cutters (high) and burned sugarcane cutters (very high). Dropouts were contacted (87%) and reported the reason for leaving work. Cross-harvest incident kidney injury (IKI) was defined as serum creatinine increase ≥0.30 mg/dL or ≥1.5 times the baseline value, or among dropouts reporting kidney injury leading to leaving work.

resultsMean cross-harvest estimated glomerular filtration rate change was significantly associated with workload, increasing from 0 mL/min/1.73 m

conclusionsWorkers considered to have the highest workload had more cross-harvest kidney damage than workers with less workload. Work practices preventing heat stress should be strengthened and their role in preventing kidney damage examined further. Future occupational studies on chronic kidney disease of unknown aetiology should account for a healthy worker effect by pursuing those lost to follow-up.

Indexed as

Acute Kidney InjuryAdultCohort StudiesCreatinineFarmersFemaleGlomerular Filtration RateHealthy Worker EffectHeat Stress DisordersHumansMaleNicaraguaOccupational DiseasesSaccharumSurveys and QuestionnairesWorkloadCreatinineCKDuHeat stressInflammationKidneyWorkload

Identifiers

PMID31611303
PMCPMC6839725
OpenAlexW2980265905

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.