Evidence map›Paper›PMID 31611280›Full record

ArticleInfection and immunity2020

Combination Immunotherapy with Passive Antibody and Sulfasalazine Accelerates Fungal Clearance and Promotes the Resolution of

Zachary Hoy, Terry W Wright, Michael Elliott, Jane Malone, Samir Bhagwat, Jing Wang, Francis Gigliotti

Open access · greenAbstract read
In one paragraph

Article in Infection and immunity, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
1.1field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Journal of fungi (Basel, Switzerland) · 2022
    Review
  6. Pathogens (Basel, Switzerland) · 2021
    Review
  7. Article
  8. Review
  9. Review
  10. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Zachary HoyDepartment of Pediatrics, Division of Infectious Diseases, University of Rochester Medical Center, Rochester, New York, USA.
Terry W WrightDepartment of Pediatrics, Division of Infectious Diseases, University of Rochester Medical Center, Rochester, New York, USA terry_wright@urmc.rochester.edu francis_gigliotti@urmc.rochester.edu.ORCID 0000-0001-6531-2214
Michael ElliottDepartment of Microbiology and Immunology, University of Rochester Medical Center, Rochester, New York, USA.
Jane MaloneDepartment of Pediatrics, Division of Infectious Diseases, University of Rochester Medical Center, Rochester, New York, USA.
Samir BhagwatDepartment of Pediatrics, Division of Infectious Diseases, University of Rochester Medical Center, Rochester, New York, USA.
Jing WangDepartment of Pediatrics, Division of Infectious Diseases, University of Rochester Medical Center, Rochester, New York, USA.
Francis GigliottiDepartment of Pediatrics, Division of Infectious Diseases, University of Rochester Medical Center, Rochester, New York, USA terry_wright@urmc.rochester.edu francis_gigliotti@urmc.rochester.edu.
University of Rochester Medical Center · US

Funding

Immunoregulatory role of CD73 in efferocytosisR01AI114554 · NIAID · UNIVERSITY OF VIRGINIA · PI ELLIOTT, MICHAEL RUSTY · 2015 to 2019
$2.5M
Passive and Active Immunization for PneumocystisR01AI117288 · NIAID · UNIVERSITY OF ROCHESTER · PI GIGLIOTTI, FRANCIS · 2016 to 2020
$2.3M
Macrophage effector functions during respiratory fungal infectionR01HL113495 · NHLBI · UNIVERSITY OF ROCHESTER · PI WRIGHT, TERRY W · 2012 to 2015
$1.5M
NHLBI NIH HHS R01 HL113495NIAID NIH HHS R01 AI114554NIAID NIH HHS R01 AI117288
6 · The paper itself

Abstract

The pulmonary immune response protects healthy individuals against

Indexed as

AnimalsAntibodiesAnti-Inflammatory AgentsCytokinesFemaleFungiImmunologic FactorsImmunomodulationImmunotherapyInflammationLungMacrophage ActivationMacrophages, AlveolarMiceMice, SCIDPhagocytosisAntibodiesAnti-Inflammatory AgentsCytokinesImmunologic FactorsSulfasalazineantifungal therapyimmunomodulationimmunopathogenesisPneumocystispulmonary infectionrespiratory pathogens

Identifiers

PMID31611280
PMCPMC6977122
OpenAlexW2980602256

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.