Evidence map›Paper›PMID 31611274›Full record

ArticleInfection and immunity2019

Dysregulation of Intestinal Microbiota Elicited by Food Allergy Induces IgA-Mediated Oral Dysbiosis.

Shohei Matsui, Hideo Kataoka, Jun-Ichi Tanaka, Mariko Kikuchi, Haruka Fukamachi, Hirobumi Morisaki, Hitomi Matsushima, Kenji Mishima, Shoji Hironaka, Takashi Takaki and 3 more

Open access · hybridAbstract read
In one paragraph

Article in Infection and immunity, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
0.7field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 20 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 2 institutions in 1 country.

Shohei MatsuiDepartment of Oral Microbiology, Showa University, Tokyo, Japan.
Hideo KataokaDepartment of Oral Microbiology, Showa University, Tokyo, Japan hideok@dent.asahi-u.ac.jp.
Jun-Ichi TanakaDepartment of Oral Diagnostic Sciences, Division of Pathology, Showa University, Tokyo, Japan.
Mariko KikuchiDepartment of Special Needs Dentistry, Division of Community-Based Comprehensive Dentistry, Showa University, Tokyo, Japan.
Haruka FukamachiDepartment of Oral Microbiology, Showa University, Tokyo, Japan.
Hirobumi MorisakiDepartment of Oral Microbiology, Showa University, Tokyo, Japan.
Hitomi MatsushimaDepartment of Pediatric Dentistry, Showa University, Tokyo, Japan.
Kenji MishimaDepartment of Oral Diagnostic Sciences, Division of Pathology, Showa University, Tokyo, Japan.
Shoji HironakaDepartment of Special Needs Dentistry, Division of Hygiene and Oral Health, Showa University, Tokyo, Japan.
Takashi TakakiDivision of Electron Microscopy, Showa University, Tokyo, Japan.
Nobuo OkahashiCenter for Frontier Oral Science, Osaka University Graduate School of Dentistry, Suita, Osaka, Japan.
Yasubumi MaruokaDepartment of Special Needs Dentistry, Division of Community-Based Comprehensive Dentistry, Showa University, Tokyo, Japan.
Hirotaka KuwataDepartment of Oral Microbiology, Showa University, Tokyo, Japan.
Showa University · JPOsaka University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Food allergy is a life-threatening response to specific foods, and microbiota imbalance (dysbiosis) in gut is considered a cause of this disease. Meanwhile, the host immune response also plays an important role in the disease. Notably, interleukin 33 (IL-33) released from damaged or necrotic intestinal epithelial cells facilitates IL-2-producing CD4 helper T (Th2) responses. However, causal relationships between the gut and oral dysbiosis and food allergy remain unknown. In this study, we analyzed effects of gut and oral dysbiosis on development of food allergy. A murine model of food allergy was established via ovalbumin (OVA) injection in BALB/c mice. Viable fecal bacteria were identified using matrix-assisted laser desorption ionization-time of flight mass spectrometry (MALDI-TOF MS).

Indexed as

DysbiosisAnimalsCytokinesDisease Models, AnimalEpithelial CellsFood HypersensitivityGastrointestinal TractImmunoglobulin AImmunologic FactorsMice, Inbred BALB CMicrobiotaMouthCytokinesImmunoglobulin AImmunologic FactorsCitrobacterfood allergymicrobiota

Identifiers

PMID31611274
PMCPMC6921656
OpenAlexW2979318536

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.