ArticleJournal of immunology (Baltimore, Md. : 1950)2019
MR1-Independent Activation of Human Mucosal-Associated Invariant T Cells by Mycobacteria.
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Article in Journal of immunology (Baltimore, Md. : 1950), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.
0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
4.4field-weighted citation impact, top 5% of its field
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
48 citing papers in PubMed, 68 citations in OpenAlex.
- Multidimensional analyses reveal modulation of adaptive and innate immune subsets by tuberculosis vaccines.Communications biology · 2020Trial
- Review
- Unconventional T cells in urological cancers: catch them if you can.Nature reviews. Urology · 2026Review
- Cytosolic delivery of bacterial metabolites by riboflavin transporters promotes MR1 antigen presentation and MAIT cell recognition.Immunology and cell biology · 2026Article
- Mucosal-Associated Invariant T Cells: Origins, Biological Functions, Diseases, and Therapeutic Targets.MedComm · 2025Review
- CD8α marks a Mycobacterium tuberculosis-reactive human NK cell population with high activation potential.Scientific reports · 2025Article
- MAIT cell homing in intestinal homeostasis and inflammation.Science advances · 2025Review
- Control of MAIT cell functions by cytokines in health and disease.Frontiers in immunology · 2025Review
- Flavin and deazaflavin biosynthesis in mycobacteria: relevance to physiology, implications for drug discovery, MR-1 antigenicity, and vaccine development.Frontiers in immunology · 2025Review
- Unveiling the immunological landscape of disseminated tuberculosis: a single-cell transcriptome perspective.Frontiers in immunology · 2025Article
- Mucosal associated invariant T cells: Powerhouses of the lung.Immunology letters · 2024Review
- Loss of circulating CD8αbioRxiv : the preprint server for biology · 2024Article
- Mucosal-associated invariant T cells in infectious diseases of respiratory system: recent advancements and applications.Journal of inflammation (London, England) · 2024Review
- Innate and Adaptive Cell-Mediated Immune Responses to a COVID-19 mRNA Vaccine in Young Children.Open forum infectious diseases · 2023Article
- Characterization of the TCRβ repertoire of peripheral MR1-restricted MAIT cells in psoriasis vulgaris patients.Scientific reports · 2023Article
- Acute inflammation alters lung lymphocytes and potentiates innate-like behavior in young mouse lung CD8 T cells, resembling lung CD8 T cells from old mice.Journal of leukocyte biology · 2023Article
- Comparative immune responses toiScience · 2023Article
- Lung epithelial cells interact with immune cells and bacteria to shape the microenvironment in tuberculosis.Thorax · 2022Review
- Dual TCR-α Expression on Mucosal-Associated Invariant T Cells as a Potential Confounder of TCR Interpretation.Journal of immunology (Baltimore, Md. : 1950) · 2022Article
- Single-Cell Transcriptional Profiling Reveals Signatures of Helper, Effector, and Regulatory MAIT Cells during Homeostasis and Activation.Journal of immunology (Baltimore, Md. : 1950) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
19 authors at 5 institutions in 2 countries.
Sara SulimanSouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa; ssuliman1@bwh.harvard.edu.ORCID 0000-0002-5154-576X
Melissa MurphySouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.ORCID 0000-0001-9906-0713
Munyaradzi MusvosviSouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.
Anele GelaSouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.
Erin W MeermeierDepartment of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239.
Hennie GeldenhuysSouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.
Christiaan HopleySouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.
Asma ToefySouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.
Nicole BilekSouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.
Ashley VeldsmanSouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.
Willem A HanekomSouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.
John L JohnsonTuberculosis Research Unit, Case Western Reserve University School of Medicine, Cleveland, OH 44106.ORCID 0000-0003-1783-0476
W Henry BoomTuberculosis Research Unit, Case Western Reserve University School of Medicine, Cleveland, OH 44106.ORCID 0000-0001-5760-9595
Gerlinde ObermoserInstitute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305; and.ORCID 0000-0003-4349-5149
Huang HuangInstitute for Immunity, Transplantation and Infection, Stanford University School of Medicine, Stanford, CA 94305; and.
Mark HatherillSouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.ORCID 0000-0003-3491-1809
David M LewinsohnDepartment of Molecular Microbiology and Immunology, Oregon Health and Science University, Portland, OR 97239.
Elisa NemesSouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.ORCID 0000-0003-1662-4961
Thomas J ScribaSouth African Tuberculosis Vaccine Initiative, University of Cape Town, Cape Town 7925, South Africa.
University of Cape Town · ZAOregon Health & Science University · USStanford University · USUniversity Hospitals of Cleveland · USBrigham and Women's Hospital · US
Funding
Tuberculosis Prevention Research Unit /TBRU/-266095383N01AI095383 · NIAID · CASE WESTERN RESERVE UNIVERSITY · 2000 to 2005
$5.6MMultidisciplinary Research Training in Pulmonary MedicineT32HL083808 · NHLBI · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., SLATORE, CHRISTOPHER G. · 2008 to 2025
$5.3MLung Resident, MR1-Restricted T Cells: Association with Differential Outcomes Following Exposure to M. TuberculosisR01AI134790 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., WALZL, GERHARD · 2018 to 2022
$3.3MHost determinants of protection against tuberculosis in adolescentsR01AI087915 · NIAID · UNIVERSITY OF CAPE TOWN · PI SCRIBA, THOMAS JENS · 2011 to 2015
$3.3MProtective immunity induced by newborn BCG vaccinationR01AI065653 · NIAID · UNIVERSITY OF CAPE TOWN · PI HANEKOM, WILLEM ALBERT · 2005 to 2009
$2.5MMemory, Phenotype, and Function of TB-reactive Human MR1 Restricted T cellsR01AI129980 · NIAID · OREGON HEALTH & SCIENCE UNIVERSITY · PI LEWINSOHN, DAVID M., LEWINSOHN, DEBORAH A. · 2019 to 2022
$2.4MNHLBI NIH HHS T32 HL083808NIAID NIH HHS N01 AI070022NIAID NIH HHS N01 AI095383NIAID NIH HHS R01 AI065653NIAID NIH HHS R01 AI087915NIAID NIH HHS R01 AI129980NIAID NIH HHS R01 AI134790
Abstract
Tuberculosis (TB) is the leading cause of mortality from a single infectious agent,
Indexed as
AdolescentChildCohort StudiesCytokinesHistocompatibility Antigens Class IHumansMinor Histocompatibility AntigensMucosal-Associated Invariant T CellsMycobacterium tuberculosisReceptors, Antigen, T-CellCytokinesHistocompatibility Antigens Class IMinor Histocompatibility AntigensMR1 protein, humanReceptors, Antigen, T-Cell
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.