Evidence map›Paper›PMID 31611074›Full record

ArticleUltrasound in medicine & biology2020

A New Multimodel Machine Learning Framework to Improve Hepatic Fibrosis Grading Using Ultrasound Elastography Systems from Different Vendors.

Isabelle Durot, Alireza Akhbardeh, Hersh Sagreiya, Andreas M Loening, Daniel L Rubin

Abstract readComparative Study
In one paragraph

Article in Ultrasound in medicine & biology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Article
  4. Article
  5. Review
  6. Review
  7. Liver fibrosis assessment: MR and US elastography.Abdominal radiology (New York) · 2022
    Review
  8. Article
  9. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Isabelle DurotDepartment of Radiology, School of Medicine, Stanford University, Stanford, California, USA; Institute of Radiology, Cantonal Hospital Aarau, Aarau, Switzerland.
Alireza AkhbardehDepartment of Radiology, School of Medicine, Stanford University, Stanford, California, USA.
Hersh SagreiyaDepartment of Radiology, School of Medicine, Stanford University, Stanford, California, USA.
Andreas M LoeningDepartment of Radiology, School of Medicine, Stanford University, Stanford, California, USA.
Daniel L RubinDepartment of Radiology, School of Medicine, Stanford University, Stanford, California, USA; Department of Biomedical Data Science, Stanford University, Stanford, California, USA; Department of Medicine (Biomedical Informatics Research), Stanford University, Stanford, California, USA. Electronic address: dlrubin@stanford.edu.

Funding

STANFORD CANCER IMAGING TRAINING (SCIT) PROGRAMT32CA009695 · NCI · STANFORD UNIVERSITY · PI BRUCE L DANIEL, Jeremy Dahl · 1993 to 2026
$7.7M
NCI NIH HHS T32 CA009695
6 · The paper itself

Abstract

The purpose of the work described here was to determine if the diagnostic performance of point and 2-D shear wave elastography (pSWE; 2-DSWE) using shear wave velocity (SWV) with a new machine learning (ML) technique applied to systems from different vendors is comparable to that of magnetic resonance elastography (MRE) in distinguishing non-significant (<F2) from significant (≥F2) fibrosis. We included two patient groups with liver disease: (i) 144 patients undergoing pSWE (Siemens) and MRE; and (ii) 60 patients undergoing 2-DSWE (Philips) and MRE. Four ML algorithms using 10 SWV measurements as inputs were trained with MRE. Results were validated using twofold cross-validation. The performance of median SWV in binary grading of fibrosis was moderate for pSWE (area under the curve [AUC]: 0.76) and 2-DSWE (0.84); the ML algorithm support vector machine (SVM) performed particularly well (pSWE: 0.96, 2-DSWE: 0.99). The results suggest that the multivendor ML-based algorithm SVM can binarily grade liver fibrosis using ultrasound elastography with excellent diagnostic performance, comparable to that of MRE.

Indexed as

Machine LearningAdultAgedAged, 80 and overElasticity Imaging TechniquesFemaleHumansLiver CirrhosisMaleMiddle AgedRetrospective StudiesYoung AdultLiver fibrosisMachine learningShear wave elastographyUltrasound

Identifiers

PMID31611074
PMCPMC6879839

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.