ArticleOphthalmology2020
Endophthalmitis after Cataract Surgery in the United States: A Report from the Intelligent Research in Sight Registry, 2013-2017.
Article in Ophthalmology, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 72 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
72 citing papers in PubMed, 2 syntheses or guidelines pooled it, 161 citations in OpenAlex.
- Impact of Patient Characteristics and Surgery-Related Risk Factors on Endophthalmitis after Cataract surgery: A Meta-Analysis.Ophthalmic research · 2025Pooled it
- Visual outcomes of acute bacterial endophthalmitis treated with adjuvant intravitreal dexamethasone: A meta-analysis and systematic review.Indian journal of ophthalmology · 2022Pooled it
- Single‑pass four‑throw versus traditional knotting pupilloplasty for traumatic mydriasis combined with lens dislocation.BMC ophthalmology · 2023Trial
- Environmental impact of cataract surgery: Responsibility, reduction, and reform.Indian journal of ophthalmology · 2026Article
- Comparative Endophthalmitis Rates in Adult and Pediatric Patients across Various Ophthalmic Procedures: An IRIS® Registry Analysis.Ophthalmology · 2026Article
- Metagenomic next-generation sequencing for comprehensive pathogen detection in intraocular infection.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2026Article
- Visual Outcomes Following Infectious Endophthalmitis from Intravitreal Injections of Biologic Drugs: An Intelligent Research in Sight Registry Retrospective Analysis.Ophthalmology and therapy · 2026Article
- Intracameral antibiotic prophylaxis and surgical expertise: key determinants in endophthalmitis after cataract surgery.International journal of retina and vitreous · 2026Article
- Incidence and clinical characteristics of acute infectious endophthalmitis after approximately 2.03 million cataract surgeries in China over a 5-year period (2017-2021).Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Article
- Artificial intelligence assisted simulation and surgical video analytics for ophthalmic surgery training and competence development.Frontiers in medicine · 2026Review
- Incidence of Endophthalmitis after Cataract Surgery in the Setting of Uveitis and Immunosuppressive Therapy within the IRIS® Registry.Ophthalmology · 2025Article
- Determinants of reoperation following cataract surgery: a real-world analysis from a large tertiary training eye hospital in Iran.International ophthalmology · 2025Article
- From Routine to Risk: Medical Liability and the Legal Implications of Cataract Surgery in the Age of Trivialization.Journal of clinical medicine · 2025Review
- Analysis of sustainability strategies in cataract surgery and surgeon perspective in reducing carbon footprint.International ophthalmology · 2025Review
- Sustainable practices in ophthalmology-steps towards environmental stewardship in healthcare.Wiener medizinische Wochenschrift (1946) · 2025Review
- Preoperative conjunctival flora and antibiotic susceptibility in cataract surgery patients at Ibn Al-Haitham teaching eye hospital in Baghdad, Iraq.Journal of ophthalmic inflammation and infection · 2025Article
- Sustainability in Cataract and Refractive Surgery: Current Challenges and Future Perspectives.Journal of ophthalmology · 2025Review
- Climate-Conscious Glaucoma Care: Strategies to Minimize the Environmental Impact in the Operating Room and in the Clinic.Journal of ophthalmology · 2025Review
- A rare case of culture-negative infective endocarditis following cataract surgery.The Journal of international medical research · 2025Article
- Myeloid Cell-Specific Deletion of AMPKα1 Worsens Ocular Bacterial Infection by Skewing Macrophage Phenotypes.Journal of immunology (Baltimore, Md. : 1950) · 2024Article
12 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 3 institutions in 1 country.
Funding
Abstract
purposeTo determine recent incidence and visual outcomes for acute-onset endophthalmitis after cataract surgery performed in the United States.
designRetrospective cohort study.
participantsUnited States cataract surgery patients, 2013-2017 (5 401 686 patients).
methodsCases of acute-onset postoperative endophthalmitis occurring within 30 days after cataract surgery were identified using diagnosis codes in the American Academy of Ophthalmology IRIS (Intelligent Research in Sight) Registry database, drawn from electronic health records in ophthalmology practices across the nation. Annual and aggregate 5-year incidences were determined for all cataract surgeries and specifically for standalone procedures versus those combined with other ophthalmic surgeries. Patient characteristics were compared. Mean and median visual acuity was determined at 1 month preoperative as well as 1 week, 1 month, and 3 months postoperative among patients with and without endophthalmitis.
main outcome measuresIncidence of acute-onset postoperative endophthalmitis after cataract surgery.
resultsA total of 8 542 838 eyes underwent cataract surgery, 3629 of which developed acute-onset endophthalmitis (0.04%; 95% confidence interval, 0.04%-0.04%). Endophthalmitis incidence was highest among patients aged 0 to 17 years (0.37% over 5 years), followed by patients aged 18 to 44 years (0.18% over 5 years; P < 0.0001). Endophthalmitis occurred 4 times more often after combined cases (cataract with other ophthalmic procedures) than after standalone cataract surgeries (0.20% vs. 0.04% of cases), and occurred in 0.35% of patients receiving anterior vitrectomy. Mean 3-month postoperative visual acuity was 20/100 (median, 20/50) among endophthalmitis patients, versus a mean of approximately 20/40 (median, 20/30) among patients without endophthalmitis. However, 4% of endophthalmitis patients still achieved 20/20 or better visual acuity, and 44% achieved 20/40 or better visual acuity at 3 months.
conclusionsAcute-onset endophthalmitis occurred in 0.04% of 8 542 838 cataract surgeries performed in the United States between 2013 and 2017. Risk factors may include younger age, cataract surgery combined with other ophthalmic surgeries, and anterior vitrectomy. Visual acuity outcomes vary; however, patients can recover excellent vision after surgery. Big data from clinical registries like the IRIS Registry has great potential for evaluating rare conditions such as endophthalmitis, including developing benchmarks, longer-term time trend investigation, and comprehensive analysis of risk factors and prophylaxis.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.