ArticleEndocrinology, diabetes & metabolism case reports2019
Pheochromocytoma arising from an ectopic adrenal tissue in multiple endocrine neoplasia type 2A.
Article in Endocrinology, diabetes & metabolism case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed, 8 citations in OpenAlex.
- Ectopic adrenal nodular hyperplasia mimicking right upper polar renal cell carcinoma: a case report and literature review.Frontiers in oncology · 2026Article
- Ectopic adrenal tissue in an inguinal hernia sac: A case report.Urology case reports · 2025Article
- Pheochromocytoma in an Ectopic Adrenal Gland.Cureus · 2023Article
- Emergence of Ectopic Adrenal Tissues-What are the Probable Mechanisms?Journal of clinical research in pediatric endocrinology · 2022Review
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Authors and funding
4 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
summaryA 21-year-old woman was referred to our hospital to treat bilateral pheochromocytomas (PCCs) after a diagnosis of multiple endocrine neoplasia type 2A (MEN2A). We performed bilateral laparoscopic adrenalectomy. One year after the operation, urinary fractionated metanephrines in 24-h urine increased. MRI showed a 30 mm tumor on the interaortocaval region and 123I-MIBG concentrated in this area. We excised the tumor and performed para-aortic lymphadenectomy. Histopathologic examination confirmed a PCC arising from ectopic adrenal tissue. Urinary fractionated metanephrines in 24-h urine declined to basal levels immediately after the operation. We detected no recurrence of paraganglioma or PCC for 5 years after the treatment. LEARNING POINTS: Most ectopic adrenal tissue is associated with no symptoms and contains only the adrenal cortex. Adrenocortical tumors sometimes arise from ectopic adrenal tissues similarly to in the normal adrenal gland. PCC arising from ectopic adrenal tissue occurs infrequently. MEN2-related PCC is accompanied by adrenal medullary hyperplasia, which might be part of tumorigenesis.
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