ArticleiScience2019
Optimal Scaling of Critical Size for Metamorphosis in the Genus Drosophila.
Article in iScience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
What it found
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Who cites it
10 citing papers in PubMed.
- A dynamical model of growth and maturation inProceedings of the National Academy of Sciences of the United States of America · 2023Article
- Mathematical modeling for developmental processes.Development, growth & differentiation · 2023Review
- Reduction of nucleolar NOC1 leads to the accumulation of pre-rRNAs and induces Xrp1, affecting growth and resulting in cell competition.Journal of cell science · 2022Article
- Drosophila Sirtuin 6 mediates developmental diet-dependent programming of adult physiology and survival.Aging cell · 2022Article
- Scaling of internal organs during Drosophila embryonic development.Biophysical journal · 2021Article
- Fitness consequences of biochemical adaptation in Drosophila melanogaster populations under simultaneous selection for faster pre-adult development and extended lifespan.Scientific reports · 2021Article
- Integrating animal development: How hormones and metabolism regulate developmental transitions and brain formation.Developmental biology · 2021Review
- TheeLife · 2020Article
- Regulation of Body Size and Growth Control.Genetics · 2020Review
- Evolution of reduced minimum critical size as a response to selection for rapid pre-adult development inRoyal Society open science · 2020Article
Corrections and comments
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Juveniles must reach a critical body size to become a mature adult. Molecular determinants of critical size have been studied, but the evolutionary importance of critical size is still unclear. Here, using nine fly species, we show that interspecific variation in organism size can be explained solely by species-specific critical size. The observed variation in critical size quantitatively agrees with the interspecific scaling relationship predicted by the life history model, which hypothesizes that critical size mediates an energy allocation switch between juvenile and adult tissues. The mechanism underlying critical size scaling is explained by an inverse relationship between growth duration and growth rate, which cancels out their contributions to the final size. Finally, we show that evolutionary changes in growth duration can be traced back to the scaling of ecdysteroid hormone dynamics. We conclude that critical size adaptively optimizes energy allocation, and has a central role in organism size determination.
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Registered trials
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