Evidence map›Paper›PMID 31610366›Full record

ArticleEnvironment international2019

Gestational diabetes mellitus, prenatal air pollution exposure, and autism spectrum disorder.

Heejoo Jo, Sandrah P Eckel, Jiu-Chiuan Chen, Myles Cockburn, Mayra P Martinez, Ting Chow, Frederick W Lurmann, William E Funk, Anny H Xiang, Rob McConnell

Abstract read
In one paragraph

Article in Environment international, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 5 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 5 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Heejoo JoDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America; Department of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, United States of America.
Sandrah P EckelDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America.
Jiu-Chiuan ChenDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America.
Myles CockburnDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America; Department of Epidemiology, University of Colorado School of Public Health, United States of America.
Mayra P MartinezDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, United States of America.
Ting ChowDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, United States of America.
Frederick W LurmannSonoma Technology, Inc., Petaluma, CA, United States of America.
William E FunkDepartment of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, IL, United States of America.
Anny H XiangDepartment of Research & Evaluation, Kaiser Permanente Southern California, Pasadena, CA, United States of America.
Rob McConnellDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles, CA, United States of America. Electronic address: rmcconne@usc.edu.

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Joseph Leo Wiemels · 1996 to 2026
$46.4M
Southern California Children's Environmental Health Center (SC-CEHC)P01ES022845 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ALLAYEE, HOOMAN · 2013 to 2018
$4.0M
The Impact of Air Pollution Exposure on COVID-19 Severity and MortalityR01ES029963 · NIEHS · KAISER FOUNDATION RESEARCH INSTITUTE · PI MCCONNELL, ROB S, XIANG, ANNY H · 2019 to 2022
$3.3M
Effects of air pollution and gestational diabetes on autismR56ES028121 · NIEHS · KAISER FOUNDATION RESEARCH INSTITUTE · PI XIANG, ANNY H · 2017 to 2017
$250k
Air pollution, gestational diabetes, and autism spectrum disorderF31ES027340 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI JO, HEEJOO · 2016 to 2018
$113k
NIEHS NIH HHS F31 ES027340NIEHS NIH HHS P01 ES022845NIEHS NIH HHS P30 ES007048NIEHS NIH HHS R01 ES029963NIEHS NIH HHS R56 ES028121
6 · The paper itself

Abstract

backgroundAmbient air pollution and maternal diabetes may affect common biological pathways underlying adverse neurodevelopmental effects. However, joint effects of maternal diabetes and air pollution on autism spectrum disorder (ASD) have not been studied.

objectiveWe evaluated whether prenatal and early-life air pollution exposure interacts with maternal diabetes status to affect ASD risk.

methodsThis retrospective cohort study included 246,420 singleton children born in Kaiser Permanente Southern California hospitals in 1999-2009. Children were followed from birth until age 5, during which 2471 ASD cases were diagnosed. Ozone (O

resultsThere were associations of ASD with preconception, first and third trimesters, and first year of life PM

conclusionsGDM onset early in pregnancy may increase children's susceptibility to prenatal O

Indexed as

Maternal ExposureAdultAir PollutantsAutism Spectrum DisorderCaliforniaChild, PreschoolCohort StudiesDiabetes, GestationalDiabetes Mellitus, Type 2FemaleHumansInfantInfant, NewbornMaleNitrogen DioxideOzoneAir PollutantsNitrogen DioxideOzoneParticulate MatterAir pollutionAutismGestational diabetes mellitusPregnancy

Identifiers

PMID31610366
PMCPMC7250244

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.