Evidence map›Paper›PMID 31609198›Full record

ArticleJournal of medical microbiology2019

Myeloid C-type lectin receptors that recognize fungal mannans interact with

Theodore J Kottom, Deanne M Hebrink, Joao T Monteiro, Bernd Lepenies, Eva M Carmona, Marcel Wuethrich, Lucas Dos Santo Dias, Andrew H Limper

Open access · greenAbstract read
In one paragraph

Article in Journal of medical microbiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 19 citations in OpenAlex.

  1. Synthetic Ligands of Myeloid C-Type Lectin Receptors.Chembiochem : a European journal of chemical biology · 2026
    Review
  2. Review
  3. Article
  4. Review
  5. Metabolic modulation:Cell surface (Amsterdam, Netherlands) · 2024
    Review
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Impact of Protein Glycosylation on the Design of Viral Vaccines.Advances in biochemical engineering/biotechnology · 2021
    Review
  12. Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 2 countries.

Theodore J KottomThoracic Diseases Research Unit, Departments of Medicine and Biochemistry, Mayo Clinic College of Medicine, Rochester, MN, 55905, USA.
Deanne M HebrinkThoracic Diseases Research Unit, Departments of Medicine and Biochemistry, Mayo Clinic College of Medicine, Rochester, MN, 55905, USA.
Joao T MonteiroImmunology Unit and Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Germany, Hannover.
Bernd LepeniesImmunology Unit and Research Center for Emerging Infections and Zoonoses, University of Veterinary Medicine, Germany, Hannover.
Eva M CarmonaThoracic Diseases Research Unit, Departments of Medicine and Biochemistry, Mayo Clinic College of Medicine, Rochester, MN, 55905, USA.
Marcel WuethrichDepartments of Pediatrics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Lucas Dos Santo DiasDepartments of Pediatrics, School of Medicine and Public Health, University of Wisconsin, Madison, WI, USA.
Andrew H LimperThoracic Diseases Research Unit, Departments of Medicine and Biochemistry, Mayo Clinic College of Medicine, Rochester, MN, 55905, USA.
Mayo Clinic · USUniversity of Veterinary Medicine Hannover, Foundation · DEUniversity of Wisconsin–Madison · US

Funding

PROTECTIVE IMMUNE RESPONSES TO BLASTOMYCES DERMATITIDISR01AI040996 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI KLEIN, BRUCE STEVEN, WUETHRICH, MARCEL · 1997 to 2023
$10.4M
Pneumocystis: Macrophage & Epithelial ActivationR01HL062150 · NHLBI · MAYO CLINIC ROCHESTER · PI ANDREW H LIMPER · 1998 to 2026
$9.2M
Regulation of vaccine-induced anti-fungal Th17 cellsR01AI093553 · NIAID · UNIVERSITY OF WISCONSIN-MADISON · PI WUETHRICH, MARCEL · 2011 to 2020
$4.5M
NHLBI NIH HHS R01 HL062150NIAID NIH HHS R01 AI040996NIAID NIH HHS R01 AI093553
6 · The paper itself

Abstract

Myeloid C-type lectin receptors (CLRs) are innate immune recognition molecules that bind to microorganisms via their carbohydrate recognition domains. In this study, we utilized a library of CLRs that recognize fungal mannans. We used this library to screen against

Indexed as

Fungal ProteinsHumansLectins, C-TypeMannansMembrane GlycoproteinsPneumocystis cariniiPneumocystis InfectionsProtein BindingFungal ProteinsLectins, C-TypeMannansMembrane GlycoproteinsC-type lectin receptorsfungiPneumocystis cariniipneumonia

Identifiers

PMID31609198
PMCPMC7363282
OpenAlexW2980943285

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.