ArticleThe EMBO journal2019
Individual cristae within the same mitochondrion display different membrane potentials and are functionally independent.
Open access · hybridAbstract read
In one paragraph
Article in The EMBO journal, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 193 papers.
0numbers the graph read from it
0cells of the map it votes in
193citing papers in PubMed
12.2field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
193 citing papers in PubMed, 311 citations in OpenAlex.
- Sprint interval exercise disrupts mitochondrial ultrastructure driving a unique mitochondrial stress response and remodelling in men.Nature communications · 2025Trial
- How mitochondrial heterogeneity fuels a dynamic organelle ecosystem.Communications biology · 2026Review
- The molecular mechanisms of crista formation: how mitochondria give themselves breathing room.Biochemical Society transactions · 2026Review
- Carbon-to-ATP ratios across the kingdoms of life.iScience · 2026Article
- Mitochondrial Cristae as Separate Compartments: Linking Organization and Function.Current issues in molecular biology · 2026Review
- A ratiometric fluorescent reporter of mitochondrial sodium.Nature chemical biology · 2026Article
- A Function-Centric Framework for Mitochondrial Quality Control.Biomolecules · 2026Review
- ATP Synthase Inhibitory Factor-1 Deficiency Attenuates Doxorubicin Cardiotoxicity by Preserving Mitochondrial Structure and Function.International journal of molecular sciences · 2026Article
- Mitochondrial calcium regulates lipid metabolism by modulating tethering of mitochondria to lipid droplets.The EMBO journal · 2026Article
- MICOS and MIMAS, multifunctional assemblies linking mitochondrial biogenesis, architecture, and function.Protein science : a publication of the Protein Society · 2026Review
- Re-evaluating the rationale for targeting oxidative phosphorylation in acute myeloid leukemia.The Biochemical journal · 2026Review
- Mechano-metabolic feedback connects tissue fluidity to mitochondrial DNA-dependent immunity in breast cancer.Nature communications · 2026Article
- FAM162A Is a Key Regulator of Mitochondrial Structure, Dynamics, and Bioenergetics, Driving Cellular Protection and Longevity.Aging cell · 2026Article
- Cristae: bridging bioenergetic hubs and compartmental barriers in mitochondrial homeostasis.Cell death & disease · 2026Review
- Membranes arrest the coarsening of mitochondrial condensates in human cells.Communications biology · 2026Article
- Programmable DNAzyme nanocatalysts orchestrate redox-immune coupling for time-gated cancer immunomodulation.Journal of nanobiotechnology · 2026Article
- Mitochondria-Derived Vesicles and Mitochondrial Extracellular Vesicles in Health and Cardiovascular Disease.Circulation research · 2026Review
- Reversal of ATP synthase is a key attribute accompanying cellular differentiation of Trypanosoma brucei insect forms.Communications biology · 2026Article
- Disturbed mitochondrial maturation in cardiolipin remodeling-deficient cardiomyocytes.iScience · 2026Article
- Microscopy in mitochondrial research - a comprehensive review.Journal of cell science · 2026Review
133 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
10 authors at 4 institutions in 2 countries.
Dane M WolfDepartment of Medicine (Endocrinology), Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Mayuko SegawaDepartment of Medicine (Endocrinology), Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Arun Kumar KondadiInstitute of Biochemistry and Molecular Biology I, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Ruchika AnandInstitute of Biochemistry and Molecular Biology I, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Sean T BaileyDepartment of Pulmonary and Critical Care Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.ORCID 0000-0001-8051-6960
Andreas S ReichertInstitute of Biochemistry and Molecular Biology I, Medical Faculty, Heinrich Heine University Düsseldorf, Düsseldorf, Germany.
Alexander M van der BliekMolecular Biology Institute at UCLA, Los Angeles, CA, USA.ORCID 0000-0002-6211-5765
David B ShackelfordDepartment of Pulmonary and Critical Care Medicine, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.
Marc LiesaDepartment of Medicine (Endocrinology), Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.ORCID 0000-0002-5909-8570
Orian S ShirihaiDepartment of Medicine (Endocrinology), Department of Molecular and Medical Pharmacology, David Geffen School of Medicine, University of California, Los Angeles, CA, USA.ORCID 0000-0001-8466-3431
University of California, Los Angeles · USHeinrich Heine University Düsseldorf · DEBoston University · USUniversity of North Carolina at Chapel Hill · US
Funding
Transgenic & Knock-out MouseP30DK063491 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI PETER J TONTONOZ · 2003 to 2026
$40.4MUCLA Pulmonary and Critical Care Medicine Training ProgramT32HL072752 · NHLBI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI JOHN A BELPERIO, TOMAS GANZ · 2003 to 2026
$8.3M(PQ5) Imaging mitochondrial heterogeneity in LKB1 mutant lung cancerR01CA208642 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI David B Shackelford · 2016 to 2026
$3.9MMitochondrial regulation of energy efficiencyR01DK099618 · NIDDK · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI CORKEY, BARBARA E., SHIRIHAI, ORIAN S · 2014 to 2018
$1.8MContributions of mitochondrial fission proteins to mitophagyU01GM109764 · NIGMS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI VAN DER BLIEK, ALEXANDER M · 2014 to 2017
$1.1MNCI NIH HHS R01 CA208642NHLBI NIH HHS T32 HL072752NIDDK NIH HHS P30 DK063491NIDDK NIH HHS R01 DK099618NIGMS NIH HHS U01 GM109764
Abstract
The mitochondrial membrane potential (ΔΨ
Indexed as
Membrane Potential, MitochondrialAdenosine TriphosphateAnimalsCarcinoma, Non-Small-Cell LungCells, CulturedFemaleHeLa CellsHumansLung NeoplasmsMaleMiceMice, Inbred C57BLMitochondriaMitochondrial MembranesMitochondrial ProteinsMyoblastsAdenosine TriphosphateMitochondrial Proteinscristaecrista junctionmembrane potentialMICOS complexOpa1
Identifiers
What OpenQuestion holds
Textmetadata
LicenceCC BY
Read underepoch 390
Registered trials
None linked
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.