Evidence map›Paper›PMID 31608598›Full record

ArticleInfluenza and other respiratory viruses2020

The burden and clinical manifestation of hospitalized influenza among different pediatric age-groups in the tropics.

Chia-Yin Chong, Chee-Fu Yung, Cherie Gan, Szu-Tien Thio, Natalie Woon-Hui Tan, Nancy Wen-Sim Tee, Cui Lin, Raymond Tze-Pin Lin, Koh-Cheng Thoon

Abstract read
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Article in Influenza and other respiratory viruses, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

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14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Article
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  5. Observational
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  11. The recent characteristics of influenza-related hospitalization in Japanese children.European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology · 2021
    Article
  12. Article
  13. [A clinical study of influenza A virus infection with neurological symptoms in children].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2021
    Article
  14. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chia-Yin ChongInfectious Diseases, Department of Paediatrics, KK Women's and Children's Hospital, Singapore.ORCID 0000-0003-3919-3324
Chee-Fu YungInfectious Diseases, Department of Paediatrics, KK Women's and Children's Hospital, Singapore.
Cherie GanSinghealth Residency Programme, Singapore General Hospital, Singapore.
Szu-Tien ThioInfectious Diseases, Department of Paediatrics, KK Women's and Children's Hospital, Singapore.
Natalie Woon-Hui TanInfectious Diseases, Department of Paediatrics, KK Women's and Children's Hospital, Singapore.
Nancy Wen-Sim TeeYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Cui LinNational Public Health Laboratory, Ministry of Health, Singapore.
Raymond Tze-Pin LinYong Loo Lin School of Medicine, National University of Singapore, Singapore.
Koh-Cheng ThoonInfectious Diseases, Department of Paediatrics, KK Women's and Children's Hospital, Singapore.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionIn tropical Singapore, influenza occurs all year-round. This study of influenza-confirmed hospitalized pediatric patients compared clinical characteristics and complications by age-group and differences between influenza A and B.

methodsThis was a retrospective study of pediatric inpatients from January 2013 to December 2014. Patients were grouped into: <6 months, 6 months to <5 years, 5- to <10-year and ≥10 years. Complications were classified into neurologic, pulmonary, and other. We also calculated the incidence of hospitalized influenza cases per 100 000 age-related population.

resultsThere were a total of 1272 patients with a median age of 37 months. The highest hospitalization rates were in the <6 months age-group. Majority (75.2%) had no comorbidity; 25.6% had complications: neurologic 11.9%, pulmonary 9.6%, other 4.1%. Patients with other complications were older, male, and had the highest influenza B rates and the longest length of stay. Influenza A comprised 76.9% of cases and had higher complication rates especially neurologic, compared to influenza B. Influenza B patients were older and were more likely to develop other complications. The 6-month to <5-year-age-group had the highest complication rate (30.6%), especially neurologic. However, ≥10 years old had the highest other complications, ICU/ high-dependency admissions and influenza B Victoria rates.

conclusionsInfants <6 months had the highest hospitalization rates for influenza. The 6-month to <5-year-age-group had the highest complication rate especially neurologic. Influenza A patients were younger, had higher seizure rates and complications compared to influenza B.

Indexed as

AdolescentAge DistributionChildChild, PreschoolFemaleHospitalizationHumansIncidenceInfantInfluenza A virusInfluenza B virusInfluenza, HumanMalePediatricsRetrospective StudiesSingaporecomplicationsdisease burdenhospitalizationsinfluenzapediatric

Identifiers

PMID31608598
PMCPMC6928028

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.