Evidence map›Paper›PMID 31608306›Full record

ArticleOptica2018

Optoacoustic imaging at kilohertz volumetric frame rates.

Ali Özbek, Xosé Luís Deán-Ben, Daniel Razansky

Abstract read
In one paragraph

Article in Optica, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed.

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  9. LED-based optoacoustic tomography of mice.Journal of biomedical optics · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Ali ÖzbekInstitute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, D-85764 Neuherberg, Germany.
Xosé Luís Deán-BenInstitute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, D-85764 Neuherberg, Germany.
Daniel RazanskyInstitute for Biological and Medical Imaging (IBMI), Helmholtz Center Munich, D-85764 Neuherberg, Germany.

Funding

Five-dimensional optoacoustic tomography for large-scale electrophysiology in scattering brainsR21EY026382 · NEI · TECHNICAL UNIVERSITY OF MUNICH · PI RAZANSKY, DANIEL · 2015 to 2016
$317k
NEI NIH HHS R21 EY026382
6 · The paper itself

Abstract

State-of-the-art optoacoustic tomographic imaging systems have been shown to attain three-dimensional (3D) frame rates of the order of 100 Hz. While such a high volumetric imaging speed is beyond reach for other bio-imaging modalities, it may still be insufficient to accurately monitor some faster events occurring on a millisecond scale. Increasing the 3D imaging rate is usually hampered by the limited throughput capacity of the data acquisition electronics and memory used to capture vast amounts of the generated optoacoustic (OA) data in real time. Herein, we developed a sparse signal acquisition scheme and a total-variation-based reconstruction approach in a combined space-time domain in order to achieve 3D OA imaging at kilohertz rates. By continuous monitoring of freely swimming zebrafish larvae in a 3D region, we demonstrate that the new approach enables significantly increasing the volumetric imaging rate by using a fraction of the tomographic projections without compromising the reconstructed image quality. The suggested method may benefit studies looking at ultrafast biological phenomena in 3D, such as large-scale neuronal activity, cardiac motion, or freely behaving organisms.

Indexed as

(100.0118) Imaging ultrafast phenomena(100.6890) Three-dimensional image processing(110.5120) Photoacoustic imaging(110.5125) Photoacoustics(320.7080) Ultrafast devices

Identifiers

PMID31608306
PMCPMC6788779

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.