Evidence map›Paper›PMID 31608247›Full record

ReviewPreventive nutrition and food science2019

Techniques for Formulation of Nanoemulsion Drug Delivery System: A Review.

Manish Kumar, Ram Singh Bishnoi, Ajay Kumar Shukla, Chandra Prakash Jain

Abstract readReview
In one paragraph

Review in Preventive nutrition and food science, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 121 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
121citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

121 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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61 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Manish KumarDepartment of Pharmacy, Mohanlal Sukhadia University, Udaipur 313001, India.
Ram Singh BishnoiDepartment of Pharmacy, Mohanlal Sukhadia University, Udaipur 313001, India.
Ajay Kumar ShuklaDepartment of Pharmacy, Mohanlal Sukhadia University, Udaipur 313001, India.
Chandra Prakash JainDepartment of Pharmacy, Mohanlal Sukhadia University, Udaipur 313001, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nanoemulsion drug delivery systems are advanced modes for delivering and improving the bioavailability of hydrophobic drugs and the drug which have high first pass metabolism. The nanoemulsion can be prepared by both high energy and low energy methods. High energy method includes high-pressure homogenization, microfluidization, and ultrasonication whereas low energy methods include the phase inversion emulsification method and the self-nanoemulsification method. Low energy methods should be preferred over high energy methods as these methods require less energy, so are more efficient and do not require any sophisticated instruments. However high energy methods are more favorable for food grade emulsion as they require lower quantities of surfactant than low energy methods. Techniques for formulation of nanoemulsion drug delivery system are overlapping in nature, especially in the case of low energy methods. In this review, we have classified different methods for formulation of nanoemulsion systems based on energy requirements, nature of phase inversion, and self-emulsification.

Indexed as

drug deliveryhigh energy methodlow energy methodnanoemulsionphase inversion methods

Identifiers

PMID31608247
PMCPMC6779084

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.