Evidence map›Paper›PMID 31608064›Full record

ArticleFrontiers in immunology2019

miR-21 Expression Determines the Early Vaccine Immunity Induced by

Sreenivas Gannavaram, Parna Bhattacharya, Abid Siddiqui, Nevien Ismail, Subha Madhavan, Hira L Nakhasi

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. iScience · 2023
    Article
  5. Article
  6. Review
  7. Article
  8. Review
  9. Review
  10. Review
  11. Revival of Leishmanization and Leishmanin.Frontiers in cellular and infection microbiology · 2021
    Review
  12. Role of Cytokines in Experimental and Human Visceral Leishmaniasis.Frontiers in cellular and infection microbiology · 2021
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Sreenivas GannavaramDivision of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, United States.
Parna BhattacharyaDivision of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, United States.
Abid SiddiquiDivision of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, United States.
Nevien IsmailDivision of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, United States.
Subha MadhavanInnovation Center for Biomedical Informatics, Georgetown University, Washington, DC, United States.
Hira L NakhasiDivision of Emerging and Transfusion Transmitted Diseases, Center for Biologics Evaluation and Research, US Food and Drug Administration, Silver Spring, MD, United States.
Center for Biologics Evaluation and Research · USUnited States Food and Drug Administration · USGeorgetown University · US

Funding

FDA HHS
6 · The paper itself

Abstract

No vaccine exists against visceral leishmaniasis. Toward developing vaccines against VL, we have reported previously on the immunogenicity of live attenuated One Sentence Summary: Role of miR-21 in vaccine induced immunity.

Indexed as

AnimalsCytokinesFemaleHumansImmunityImmunizationLeishmania donovaniLeishmaniasis VaccinesLeishmaniasis, VisceralMacrophagesMice, Inbred C57BLMice, KnockoutMice, TransgenicMicroRNAsTh1 CellsVaccines, AttenuatedCytokinesLeishmaniasis VaccinesMicroRNAsMIRN21 microRNA, mouseVaccines, AttenuatedbiomarkerIL-12leishmaniasislive attenuated Leishmania vaccinesmicroRNAmiR-21parasitic vaccines

Identifiers

PMID31608064
PMCPMC6769120
OpenAlexW2975563476

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.