Evidence map›Paper›PMID 31608063›Full record

ArticleFrontiers in immunology2019

WASp Is Essential for Effector-to-Memory conversion and for Maintenance of CD8

Qiao Liu, Liang Zhang, Zhou Shu, Tingting Yu, Lina Zhou, Wenxia Song, Xiaodong Zhao

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in immunology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.4field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 8 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Qiao LiuChongqing Key Laboratory of Child Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China.
Liang ZhangChongqing Key Laboratory of Child Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China.
Zhou ShuDivision of Immunology, Children's Hospital of Chongqing Medical University, Chongqing, China.
Tingting YuChongqing Key Laboratory of Child Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China.
Lina ZhouChongqing Key Laboratory of Child Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China.
Wenxia SongDepartment of Cell Biology and Molecular Genetics, University of Maryland, College Park, MD, United States.
Xiaodong ZhaoChongqing Key Laboratory of Child Infection and Immunity, Children's Hospital of Chongqing Medical University, Chongqing, China.
Chongqing Medical University · CNChildren's Hospital of Chongqing Medical University · CNUniversity of Maryland, College Park · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wiskott-Aldrich syndrome (WAS) is a rare X-linked primary immunodeficiency characterized by recurrent infections, micro thrombocytopenia, eczema, and a high incidence of autoimmunity and malignancy. A defect in the T cell compartment is thought to be a major cause of immunodeficiency in patients with WAS; However, whether the antigen specific T memory cell is altered has not been extensively studied. Here, we examined the expansion/contraction kinetics of CD8

Indexed as

AnimalsApoptosisCD8-Positive T-LymphocytesCell DifferentiationCell ProliferationCytokinesHumansImmunologic MemoryLymphocytic ChoriomeningitisLymphocytic choriomeningitis virusMiceMice, KnockoutSialic Acid Binding Ig-like Lectin 3Wiskott-Aldrich Syndrome ProteinCytokinesSialic Acid Binding Ig-like Lectin 3Wiskott-Aldrich Syndrome ProteinCD8 T cellskineticsmemoryrecall responseWiskott-Aldrich syndrome

Identifiers

PMID31608063
PMCPMC6769127
OpenAlexW2976593107

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.