Evidence map›Paper›PMID 31607948›Full record

ArticleFrontiers in physiology2019

Depiction of Physiological Homeostasis by Self-Coupled System and Its Significance.

Xia Lu, Guantao Jin, Wenjin Chen, Xinguang Yu, Feng Ling

Abstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Xia LuDepartment of Neurosurgery, Chinese PLA General Hospital and Medical School of Chinese PLA, Beijing, China.
Guantao JinAdvanced School of Art and Humanities, Chinese Academy of Art, Hangzhou, China.
Wenjin ChenDepartment of Neurosurgery, Xuanwu Hospital Capital Medical University and China International Institution of Neuroscience, Beijing, China.
Xinguang YuDepartment of Neurosurgery, Chinese PLA General Hospital and Medical School of Chinese PLA, Beijing, China.
Feng LingDepartment of Neurosurgery, Xuanwu Hospital Capital Medical University and China International Institution of Neuroscience, Beijing, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The negative feedback system (NFS) was regarded as the basic unit of regulation of physiological homeostasis for more than 70 years. However, NFS-based depiction possesses some limitations. The self-coupled system (SCS), a non-stop system in which the output of the current moment becomes the input of the next moment, can also be utilized to depict homeostasis. In SCS-based depiction, all of the related regulatory mechanisms of a homeostasis are regarded as an entity. Then, homeostatic dynamics can be expressed by simple mathematical language. A new disease group was revealed and some useful inferences were obtained through mathematical deduction. They were supported by published studies. SCS-based depiction of homeostasis should be a requisite supplement to medical knowledge systems based on NFS.

Indexed as

continuous monitoringhomeostasis maintenancenegative feedback systemself-coupled systemweakened regulatory function induced disease

Identifiers

PMID31607948
PMCPMC6761279

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.