Evidence map›Paper›PMID 31607937›Full record

ArticleFrontiers in physiology2019

Excessive Accumulation of Ca

Marta Canato, Paola Capitanio, Lina Cancellara, Luigi Leanza, Anna Raffaello, Denis Vecellio Reane, Lorenzo Marcucci, Antonio Michelucci, Feliciano Protasi, Carlo Reggiani

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
0.9field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 25 citations in OpenAlex.

  1. Exercise capacity in RYR1-related myopathies.Orphanet journal of rare diseases · 2025
    Trial
  2. Article
  3. Article
  4. Article
  5. Phosphorylation of RYR1 at SerScience signaling · 2025
    Article
  6. Article
  7. Article
  8. Review
  9. Cytosolic CaBiophysical reports · 2023
    Article
  10. Article
  11. Review
  12. Review
  13. Article
  14. Article
  15. Altered CaMetabolites · 2021
    Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Marta CanatoDepartment of Biomedical Sciences, School of Medicine and Surgery, University of Padova, Padua, Italy.
Paola CapitanioDepartment of Biomedical Sciences, School of Medicine and Surgery, University of Padova, Padua, Italy.
Lina CancellaraDepartment of Biomedical Sciences, School of Medicine and Surgery, University of Padova, Padua, Italy.
Luigi LeanzaDepartment of Biology, University of Padova, Padua, Italy.
Anna RaffaelloDepartment of Biomedical Sciences, School of Medicine and Surgery, University of Padova, Padua, Italy.
Denis Vecellio ReaneDepartment of Biomedical Sciences, School of Medicine and Surgery, University of Padova, Padua, Italy.
Lorenzo MarcucciDepartment of Biomedical Sciences, School of Medicine and Surgery, University of Padova, Padua, Italy.
Antonio MichelucciCenter for Advanced Studies and Technology, Università degli Studi "G. d'Annunzio" Chieti-Pescara, Chieti, Italy.
Feliciano ProtasiCenter for Advanced Studies and Technology, Università degli Studi "G. d'Annunzio" Chieti-Pescara, Chieti, Italy.
Carlo ReggianiDepartment of Biomedical Sciences, School of Medicine and Surgery, University of Padova, Padua, Italy.
University of Padua · ITUniversity of Chieti-Pescara · IT

Funding

Molecular Mechanism and Functional Role of SOCE in Skeletal MuscleR01AR059646 · NIAMS · UNIVERSITY OF ROCHESTER · PI DIRKSEN, ROBERT T · 2010 to 2020
$3.6M
NIAMS NIH HHS R01 AR059646
6 · The paper itself

Abstract

Mice (Y522S or YS), carrying a mutation of the sarcoplasmic reticulum (SR) Ca

Indexed as

excitation–contraction couplingmalignant hyperthermiamitochondriareactive oxygen speciesryanodine receptor

Identifiers

PMID31607937
PMCPMC6755340
OpenAlexW2969469491

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.