Evidence map›Paper›PMID 31607908›Full record

ArticleFrontiers in pharmacology2019

Yizhiqingxin Formula Alleviates Cognitive Deficits and Enhances Autophagy

Yang Yang, Zhiyong Wang, Yu Cao, Jiangang Liu, Peng Li, Hao Li, Meixia Liu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in pharmacology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
2.1field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 22 citations in OpenAlex.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Yang YangInstitute of Geriatrics, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Zhiyong WangInstitute of Geriatrics, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Yu CaoInstitute of Geriatrics, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Jiangang LiuInstitute of Geriatrics, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Peng LiBeijing Key Laboratory of Pharmacology of Chinese Materia Region, Institute of Basic Medical Sciences of Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Hao LiInstitute of Geriatrics, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Meixia LiuInstitute of Geriatrics, Xiyuan Hospital, China Academy of Chinese Medical Sciences, Beijing, China.
Chinese Academy of Medical Sciences & Peking Union Medical College · CNXiyuan Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alzheimer's disease (AD) is the most common type of dementia worldwide. The deposition of amyloid β (Aβ) is one of the most important pathological changes in AD. Autophagy, which mediates degradation of toxic proteins and maintains normal neuronal function, is dysfunctional in AD; dysfunctional autophagy is believed to be a critical pathological feature of AD. Here, we evaluated the

Indexed as

Alzheimer’s diseaseAPP/PS1 miceautophagymTORYizhiqingxin formula

Identifiers

PMID31607908
PMCPMC6758600
OpenAlexW2968910435

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.