ArticleFrontiers in human neuroscience2019
Relationship Between Integrity of the Corpus Callosum and Bimanual Coordination in Children With Unilateral Spastic Cerebral Palsy.
Article in Frontiers in human neuroscience, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 3 of them syntheses that pooled it.
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Who cites it
17 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- White matter lesions and DTI metrics related to various types of dysfunction in cerebral palsy: A meta-analysis and systematic review.PloS one · 2025Pooled it
- A systematic review of instrumented assessments for upper limb function in cerebral palsy: current limitations and future directions.Journal of neuroengineering and rehabilitation · 2024Pooled it
- Bimanual movements in children with cerebral palsy: a systematic review of instrumented assessments.Journal of neuroengineering and rehabilitation · 2023Pooled it
- Structural brain correlates of balance control in children with cerebral palsy: baseline correlations and effects of training.Brain structure & function · 2025Trial
- Corpus Callosum Integrity Relates to Improvement of Upper-Extremity Function Following Intensive Rehabilitation in Children With Unilateral Spastic Cerebral Palsy.Neurorehabilitation and neural repair · 2021Trial
- Age-related differences in behavioral outcomes of bimanual functional motor tasks in children and adolescents with cerebral palsy: a scoping review.Disability and rehabilitation · 2025Article
- Feedforward control in children with cerebral palsy and association with white matter integrity.Frontiers in neurology · 2025Article
- Robotic assessment of bilateral and unilateral upper limb functions in adults with cerebral palsy.Journal of neuroengineering and rehabilitation · 2024Article
- Corpus callosum long-term biometry in very preterm children related to cognitive and motor outcomes.Pediatric research · 2024Article
- Corpus Callosum Functional Activities in Children with Cerebral Palsy.Journal of biomedical physics & engineering · 2024Article
- In-depth quantification of bimanual coordination using the Kinarm exoskeleton robot in children with unilateral cerebral palsy.Journal of neuroengineering and rehabilitation · 2023Article
- Altered corpus callosum structure in adolescents with cerebral palsy: connection to gait and balance.Brain structure & function · 2023Article
- The Challenge of Diffusion Magnetic Resonance Imaging in Cerebral Palsy: A Proposed Method to Identify White Matter Pathways.Brain sciences · 2023Article
- White matter microstructure and receptive vocabulary in children with cerebral palsy: The role of interhemispheric connectivity.PloS one · 2023Article
- Bimanual motor impairments in older adults: an updated systematic review and meta-analysis.EXCLI journal · 2022Review
- Upper Limb Motor Planning in Individuals with Cerebral Palsy Aged between 3 and 21 Years Old: A Systematic Review.Brain sciences · 2021Review
- Impact of Sensory Deficits on Upper Limb Motor Performance in Individuals with Cerebral Palsy: A Systematic Review.Brain sciences · 2021Review
Corrections and comments
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Children with unilateral spastic cerebral palsy (USCP) have shown impaired bimanual coordination. The corpus callosum (CC) connects the two hemispheres and is critical for tasks that require inter-hemisphere communication. The relationship between the functional bimanual coordination impairments and structural integrity of the CC is unclear. We hypothesized that better integrity of the CC would relate to better bimanual coordination performance during a kinematic bimanual drawer-opening task. Thirty-nine children with USCP (Age: 6-17 years old; MACS levels: I-III) participated in the study. Measurement of the CC integrity was performed using diffusion tensor imaging. The CC was measured as a whole and was also divided into three regions: genu, midbody, and splenium. Fractional anisotropy, axial diffusivity (AD), radial diffusivity, mean diffusivity, number of voxels, and number of streamlines were evaluated in whole and within each region of the CC. 3-D kinematic analyses of bimanual coordination were also assessed while children performed the bimanual task. There were negative correlations between bimanual coordination measures of total movement time and AD of whole CC (
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