ArticleReproductive medicine and biology2019
Does sperm DNA fragmentation correlate with semen parameters?
Article in Reproductive medicine and biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 1 of them a synthesis that pooled it.
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Who cites it
43 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Meta-correlation of Sperm Morphology and DNA Fragmentation Index.Reproductive sciences (Thousand Oaks, Calif.) · 2025Pooled it
- Optimizing outcomes in intrauterine insemination: A narrative synthesis of two decades of clinical research (2000-2024).International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2026Review
- Microplastics and male reproductive system: A comprehensive review based on cellular and molecular effects.Toxicology reports · 2026Review
- Single-Molecule approach to quantify sperm single-stranded DNA damage using the novel sperm repair-assisted damage detection (SRADD) assay.Journal of assisted reproduction and genetics · 2026Article
- Stigmasterol restores testicular and sperm function in ICR mice exposed to high oxidative stress condition.Die Naturwissenschaften · 2026Article
- Sperm DNA fragmentation index did not associate with assisted reproductive outcomes: a cohort retrospective study of 5784 IVF/ICSI cycles.Journal of assisted reproduction and genetics · 2025Article
- Relationship Between Vitamin D Level and DNA Fragmentation Index of Sperm in Men Referred to Omid Infertility Center in Hamadan-Iran: A Cross-Sectional Study.Journal of family & reproductive health · 2025Article
- Developing a simple universal hypo-osmotic swelling test (HOST) for assessing sperm membrane integrity in pigs, rabbits, and goats.Journal of advanced veterinary and animal research · 2025Article
- Abnormal sperm tails correlate with the sperm DNA fragmentation index, irrespective of progressive motility, according to an analysis of 5125 semen reports.Journal of assisted reproduction and genetics · 2025Article
- Embryology outcomes of a device-based sperm separation technique compared to density gradient centrifugation using thawed spermatozoa-a sibling donor oocyte study.Journal of assisted reproduction and genetics · 2025Article
- Evaluation of seminal plasma levels of vaspin and visfatin in infertile males with elevated sperm DNA fragmentation index: a comparative study.Basic and clinical andrology · 2024Article
- Sperm DNA Fragmentation: Unraveling Its Imperative Impact on Male Infertility Based on Recent Evidence.International journal of molecular sciences · 2024Review
- Article
- A loss-of-function variant in ZCWPW1 causes human male infertility with sperm head defect and high DNA fragmentation.Reproductive health · 2024Article
- Sperm DNA fragmentation index affect pregnancy outcomes and offspring safety in assisted reproductive technology.Scientific reports · 2024Article
- Repair mechanism of Yishen Tongluo formula on mouse sperm DNA fragmentation caused by polystyrene microplastics.Pharmaceutical biology · 2023Article
- Can a sperm selection technique improve embryo ploidy?Andrology · 2023Article
- Impact of semen oxidative stress on sperm quality: initial results from Vietnam.The Journal of international medical research · 2023Article
- Performing a sperm DNA fragmentation test in addition to semen examination based on the WHO criteria can be a more accurate diagnosis of IVF outcomes.BMC urology · 2023Article
- How Well Do Semen Analysis Parameters Correlate with Sperm DNA Fragmentation? A Retrospective Study from 2567 Semen Samples Analyzed by the Halosperm Test.Journal of personalized medicine · 2023Article
Corrections and comments
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Authors and funding
8 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to investigate the association between sperm quality assessed by routine semen analysis and sperm DNA integrity assay.
methodsIn our cross-sectional study, a total of 318 men from the infertile couples were enrolled from December 2017 to March 2019 at the Hue Center for Reproductive Endocrinology and Infertility, Vietnam. General characteristics and semen parameters were detected. The sperm DNA fragmentation index (DFI) was estimated by the sperm chromatin dispersion (SCD) assay. A threshold of DFI 30% was applied to classify normal (DFI < 30%) or abnormal (DFI ≥ 30%) groups. The correlations between DFI and semen parameters were analyzed by Spearman's rank correlation coefficient.
resultsIn the correlation analysis, DFI was significantly correlated with abnormal head and progressive motility, with a positive correlation with abnormal head (
conclusionsThe sperm DFI was not strongly correlated with conventional semen parameters. Therefore, a sperm DNA fragmentation assay should be performed as an additional step in the investigation of male fertility.
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