Evidence map›Paper›PMID 31607174›Full record

ArticleHypertension (Dallas, Tex. : 1979)2019

Exercise Pressor Reflex Contributes to the Cardiovascular Abnormalities Characterizing: Hypertensive Humans During Exercise.

Simranjit K Sidhu, Joshua C Weavil, Matthew J Rossman, Jacob E Jessop, Amber D Bledsoe, Michael J Buys, Mark S Supiano, Russell S Richardson, Markus Amann

Open access · bronzeAbstract read
In one paragraph

Article in Hypertension (Dallas, Tex. : 1979), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
2.1field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 23 citations in OpenAlex.

  1. Trial
  2. Article
  3. Obligatory neural feedback control of exercise cardiorespiratory function and performance.Journal of applied physiology (Bethesda, Md. : 1985) · 2025
    Review
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Hypertension restricts leg blood flow and aggravates neuromuscular fatigue during human locomotion in males.American journal of physiology. Regulatory, integrative and comparative physiology · 2024
    Article
  10. Review
  11. Review
  12. Article
  13. Gene and protein expression of dorsal root ganglion sensory receptors in normotensive and hypertensive male rats.American journal of physiology. Regulatory, integrative and comparative physiology · 2022
    Article
  14. Article
  15. The exercise pressor reflex: An update.Clinical autonomic research : official journal of the Clinical Autonomic Research Society · 2022
    Review
  16. Review
  17. Article
  18. Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Simranjit K SidhuFrom the Department of Internal Medicine, Division of Geriatrics (S.K.S., M.J.R., M.S.S., R.S.R., M.A.), University of Utah, Salt Lake City.
Joshua C WeavilGeriatric Research, Education, and Clinical Center, VAMC Salt Lake City, UT (J.C.W., M.S.S., R.S.R., M.A.).
Matthew J RossmanFrom the Department of Internal Medicine, Division of Geriatrics (S.K.S., M.J.R., M.S.S., R.S.R., M.A.), University of Utah, Salt Lake City.
Jacob E JessopDepartment of Anesthesiology (J.E.J., A.D.B., M.J.B., M.A.), University of Utah, Salt Lake City.
Amber D BledsoeDepartment of Anesthesiology (J.E.J., A.D.B., M.J.B., M.A.), University of Utah, Salt Lake City.
Michael J BuysDepartment of Anesthesiology (J.E.J., A.D.B., M.J.B., M.A.), University of Utah, Salt Lake City.
Mark S SupianoFrom the Department of Internal Medicine, Division of Geriatrics (S.K.S., M.J.R., M.S.S., R.S.R., M.A.), University of Utah, Salt Lake City.
Russell S RichardsonFrom the Department of Internal Medicine, Division of Geriatrics (S.K.S., M.J.R., M.S.S., R.S.R., M.A.), University of Utah, Salt Lake City.
Markus AmannFrom the Department of Internal Medicine, Division of Geriatrics (S.K.S., M.J.R., M.S.S., R.S.R., M.A.), University of Utah, Salt Lake City.
University of Utah · USGeriatric Research Education and Clinical Center · US

Funding

Role of Sensory Neurons in Human Cardiovascular DiseaseR01HL116579 · NHLBI · UNIVERSITY OF UTAH · PI AMANN, MARKUS · 2013 to 2021
$3.4M
NHLBI NIH HHS R01 HL116579
6 · The paper itself

Abstract

We investigated the impact of hypertension on circulatory responses to exercise and the role of the exercise pressor reflex in determining the cardiovascular abnormalities characterizing patients with hypertension. After a 7-day drug washout, 8 hypertensive (mean arterial pressure [MAP] 130±4 mm Hg; 65±3 years) and 8 normotensive (MAP 117±2 mm Hg; 65±2 years) individuals performed single-leg knee-extensor exercise (7 W, 15 W, 50%, 80%-W

Indexed as

AgedArterial PressureBlood Flow VelocityBlood Pressure DeterminationCardiovascular AbnormalitiesCase-Control StudiesExerciseFemaleHemodynamicsHumansHypertensionMaleMiddle AgedMuscle ContractionPressoreceptorsReference Valuesblood pressurecardiovascular diseaseexercisehypertensionreflex

Identifiers

PMID31607174
PMCPMC6854322
OpenAlexW2980181058

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.