Evidence map›Paper›PMID 31607148›Full record

Observational studyCirculation. Arrhythmia and electrophysiology2019

Prevalence and Characteristics of Subclinical Atrial Fibrillation in a Community-Dwelling Elderly Population: The ARIC Study.

Mary R Rooney, Elsayed Z Soliman, Pamela L Lutsey, Faye L Norby, Laura R Loehr, Thomas H Mosley, Michael Zhang, Rebecca F Gottesman, Josef Coresh, Aaron R Folsom and 2 more

Open access · bronzeAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Circulation. Arrhythmia and electrophysiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 50 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
50citing papers in PubMed, 1 pooled it
6.4field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

50 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

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  16. Multimodal data integration to predict atrial fibrillation.European heart journal. Digital health · 2025
    Article
  17. Association of Left Atrial Function With Incident Chronic Kidney Disease in Older Adults.Mayo Clinic proceedings. Innovations, quality & outcomes · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 1 institution in 1 country.

Mary R RooneyDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis (M.R.R., P.L.L., F.L.N., A.R.F.).
Elsayed Z SolimanEpidemiological Cardiology Research Center (EPICARE), School of Medicine, Wake Forest University, Winston-Salem (E.Z.S.).
Pamela L LutseyDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis (M.R.R., P.L.L., F.L.N., A.R.F.).
Faye L NorbyDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis (M.R.R., P.L.L., F.L.N., A.R.F.).
Laura R LoehrDepartment of Epidemiology, Gillings School of Public Health, University of North Carolina, Chapel-Hill (L.R.L.).
Thomas H MosleyThe MIND Center, University of Mississippi Medical Center, Jackson (T.H.M.).
Michael ZhangCardiac Arrhythmia Center, Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis (M.Z., L.Y.C.).
Rebecca F GottesmanDepartment of Epidemiology, Bloomberg School of Public Health (M.R.R., R.F.G., J.C.), Johns Hopkins University, Baltimore, MD.
Josef CoreshDepartment of Epidemiology, Bloomberg School of Public Health (M.R.R., R.F.G., J.C.), Johns Hopkins University, Baltimore, MD.
Aaron R FolsomDivision of Epidemiology and Community Health, School of Public Health, University of Minnesota, Minneapolis (M.R.R., P.L.L., F.L.N., A.R.F.).
Alvaro AlonsoDepartment of Epidemiology, Rollins School of Public Health, Emory University, Atlanta, GA (A.A.).
Lin Y ChenCardiac Arrhythmia Center, Cardiovascular Division, Department of Medicine, University of Minnesota Medical School, Minneapolis (M.Z., L.Y.C.).
Emory University · US

Funding

Cardiovascular Disease Epidemiology &Prevention TrngT32HL007779 · NHLBI · UNIVERSITY OF MINNESOTA TWIN CITIES · PI PAMELA L. Lutsey, JAMES S PANKOW · 1994 to 2026
$9.3M
Significance of Atrial Fibrillation and Atrial Fibrillation Burden Detected by Novel ECG Monitoring in Community-Dwelling ElderlyR01HL126637 · NHLBI · UNIVERSITY OF MINNESOTA · PI CHEN, LIN YEE · 2016 to 2020
$3.7M
Left Atrial Abnormality and Atrial Fibrillation-Related Cerebral Infarcts and Cognitive DeclineR01HL141288 · NHLBI · UNIVERSITY OF MINNESOTA · PI CHEN, LIN YEE · 2018 to 2021
$2.1M
Mentoring in patient-oriented atrial fibrillation and cardiovascular researchK24HL148521 · NHLBI · EMORY UNIVERSITY · PI ALONSO, ALVARO · 2019 to 2023
$593k
American Heart Association-American Stroke Association 16EIA26410001NHLBI NIH HHS HHSN268201700001CNHLBI NIH HHS HHSN268201700001INHLBI NIH HHS HHSN268201700002CNHLBI NIH HHS HHSN268201700002INHLBI NIH HHS HHSN268201700003CNHLBI NIH HHS HHSN268201700003INHLBI NIH HHS HHSN268201700004CNHLBI NIH HHS HHSN268201700004INHLBI NIH HHS HHSN268201700005CNHLBI NIH HHS HHSN268201700005INHLBI NIH HHS K24 HL148521NHLBI NIH HHS R01 HL126637NHLBI NIH HHS R01 HL141288NHLBI NIH HHS T32 HL007779
6 · The paper itself

Abstract

backgroundThe prevalence of subclinical atrial fibrillation (AF) in the elderly general population is unclear. We sought to define the prevalence of subclinical AF in a community-based elderly population and to characterize subclinical AF and the incremental diagnostic yield of 4 versus 2 weeks of continuous ECG monitoring.

methodsWe conducted a cross-sectional analysis within the community-based multicenter observational ARIC study (Atherosclerosis Risk in Communities) using visit 6 (2016-2017) data. The 2616 ARIC study participants who wore a leadless, ambulatory ECG monitor (Zio XT Patch) for up to 2 weeks were aged 79±5 years, 42% men, and 26% black. In a subset, 386 participants without clinically recognized AF wore the monitor twice, each time for up to 2 weeks. We characterized the prevalence of subclinical AF (ie, AF detected on the Zio XT Patch without clinically recognized AF) over 2 weeks of monitoring and the diagnostic yield of 4 versus 2 weeks of monitoring.

resultsThe prevalence of subclinical AF was 2.5%; the prevalence of subclinical AF was 3.3% among white men, 2.5% among white women, 2.1% among black men, and 1.6% among black women. Subclinical AF was mostly intermittent (75%). Among those with intermittent subclinical AF, 91% had AF burden ≤10% during the monitoring period. In a subset of 386 participants without clinical AF, 78% more subclinical AF was detected by 4 weeks versus 2 weeks of ECG monitoring.

conclusionsIn our study, the prevalence of subclinical AF was lower than previously reported and monitoring beyond 2 weeks provided substantial incremental diagnostic yield. Future studies should focus on individuals with higher risk to increase diagnostic yield and consider continuous monitoring duration longer than 2 weeks.

Indexed as

ElectrocardiographyIndependent LivingAgedAged, 80 and overAtrial FibrillationCross-Sectional StudiesFemaleFollow-Up StudiesHumansMaleMiddle AgedPrevalenceRetrospective StudiesRisk FactorsUnited Statesatrial fibrillationelderlyelectrocardiographyprevalence

Identifiers

PMID31607148
PMCPMC6814387
OpenAlexW2979567406

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.