Evidence map›Paper›PMID 31607071›Full record

ArticleNeurospine2019

Cervical Spondylotic Myelopathy: Natural Course and the Value of Diagnostic Techniques -WFNS Spine Committee Recommendations.

Mehmet Zileli, Sachin A Borkar, Sumit Sinha, Rui Reinas, Óscar L Alves, Se-Hoon Kim, Sumeet Pawar, Bala Murali, Jutty Parthiban

Open access · diamondAbstract read
In one paragraph

Article in Neurospine, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 38 papers.

0numbers the graph read from it
0cells of the map it votes in
38citing papers in PubMed
4.9field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

38 citing papers in PubMed, 63 citations in OpenAlex.

  1. Comparative clinical outcomes of ACDF for cervical spondylotic myelopathy versus atypical cervical pathology presenting as refractory low back pain with radiating lower limb pain: a retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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  6. Conservative and newer drug treatment for degenerative cervical myelopathy.Journal of clinical orthopaedics and trauma · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 4 countries.

Mehmet ZileliDepartment of Neurosurgery, Ege University, Izmir, Turkey.
Sachin A BorkarDepartment of Neurosurgery, All India Institute of Medical Sciences, New Delhi, India.
Sumit SinhaNeurosurgery and Spine Services, Paras Hospitals, Gurugram, India.
Rui ReinasNeurosurgical Department, Centro Hospitalar Vila Nova de Gaia/Espinho, Hospital Lusíadas, Porto, Portugal.
Óscar L AlvesDepartment of Neurosurgery, Hospital Lusíadas, Porto, Portugal.
Se-Hoon KimDepartment of Neurosurgery, Korea University Ansan Hospital, Korea University Medical Center, Seoul, Korea.
Sumeet PawarSRCC Children's Hospital, Mumbai, India.
Bala MuraliKauvery Advanced Spine Centre, Chennai, India.
Jutty ParthibanDepartment Neurosurgery and Spine Unit, Kovai Medical Center and Hospital, Tamilnadu, India.
All India Institute of Medical Sciences · INCentro Hospitalar de Vila Nova de Gaia · PTEge University · TRKorea University Medical Center · KRKovai Medical Center and Hospital · INLusíada University of Porto · PTParas Hospitals · INSRCC Children’s Hospital · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThis study presents the results of a systematic literature review conducted to determine most up-to-date information on the natural outcome of cervical spondylotic myelopathy (CSM) and the most reliable diagnostic techniques.

methodsA literature search was performed for articles published during the last 10 years.

resultsThe natural course of patients with cervical stenosis and signs of myelopathy is quite variable. In patients with no symptoms, but significant stenosis, the risk of developing myelopathy with cervical stenosis is approximately 3% per year. Myelopathic signs are useful for the clinical diagnosis of CSM. However, they are not highly sensitive and may be absent in approximately one-fifth of patients with myelopathy. The electrophysiological tests to be used in CSM patients are motor evoked potential (MEP), spinal cord evoked potential, somatosensory evoked potential, and electromyography (EMG). The differential diagnosis of CSM from other neurological conditions can be accomplished by those tests. MEP and EMG monitoring are useful to reduce C5 root palsy during CSM surgery. Notable spinal cord T2 hyperintensity on cervical magnetic resonance imaging (MRI) is correlated with a worse outcome, whereas lighter signal changes may predict better outcomes. T1 hypointensity should be considered a sign of more advanced disease.

conclusionThe natural course of CSM is quite variable. Signal changes on MRI and some electrophysiological tests are valuable adjuncts to diagnosis.

Indexed as

Cervical spondylotic myelopathyElectrophysiologyIntraoperative monitoringMagnetic resonance imagingMR signal intensityMyelopathic signs

Identifiers

PMID31607071
PMCPMC6790728
OpenAlexW2975577546

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.