SynthesisThe Lancet. Child & adolescent health2019
The relationship between pain and suicidal vulnerability in adolescence: a systematic review.
Synthesis in The Lancet. Child & adolescent health, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
21 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Factors Associated with Suicidal Behavior in Adolescents: An Umbrella Review Using the Socio-Ecological Model.Community mental health journal · 2025Pooled it
- Prevalence of suicidal behavior in patients with chronic pain: a systematic review and meta-analysis of observational studies.Frontiers in psychology · 2023Pooled it
- Prevalence and Correlates of Suicidal Distress in Adolescents in a Chronic Pain Service.Paediatric & neonatal pain · 2026Article
- Symptom network analysis of depressive and somatic symptoms and suicide risk indicators in treatment-naïve adolescents with first-episode depression.BMC psychiatry · 2026Article
- Article
- Dysmenorrhea and Adolescent Mental Health: A School-Based Cross-Sectional Study.BJOG : an international journal of obstetrics and gynaecology · 2025Article
- Estimating the longitudinal association between pain characteristics and clinical outcomes in young people with mental ill-health.Psychological medicine · 2025Article
- Associations between somatic symptoms and suicidal behavior: a cohort study in Chinese adolescents.BMC psychology · 2025Article
- Cyberbullying victimization and suicidal ideation among college students: the mediating role of psychological pain and the moderating role of school bonding.BMC psychiatry · 2025Article
- Proposition of Two Subtypes of Patients at Risk of Suicide: Pain Hypersensitive Vs. Dissociative.Current psychiatry reports · 2025Review
- Suicidal Ideation and Attempts Among Youth With Physical-Mental Comorbidity in Canada: Proposal for an Epidemiological Study.JMIR research protocols · 2024Article
- Unveiling Adolescent Suicidality: Holistic Analysis of Protective and Risk Factors Using Multiple Machine Learning Algorithms.Journal of youth and adolescence · 2024Article
- Suicidal Thoughts and Trajectories of Psychopathological and Behavioral Symptoms in Adolescence.JAMA network open · 2024Article
- Observational
- Pain and suicidality in children and adolescents: a longitudinal population-based study.European child & adolescent psychiatry · 2023Article
- Identifying and Managing Suicidality in Children and Adolescents with Chronic Pain: Evidence-Based Treatment Strategies.Psychology research and behavior management · 2022Review
- Transitional Pain Care in Quebec: Did We Forget Our Youths? A Brief Research Report.Frontiers in pain research (Lausanne, Switzerland) · 2022Article
- Associations of frequent pain symptoms with excessive daytime sleepiness in adolescents: a longitudinal study.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2021Article
- Does depression moderate the relationship between pain and suicidality in adolescence? A moderated network analysis.Journal of affective disorders · 2021Article
- The Association Between Psychological Symptoms and Self-Reported Temporomandibular Disorders Pain Symptoms in Children and Adolescents.Frontiers in oral health · 2021Article
Corrections and comments
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Authors and funding
6 authors.
Funding
Abstract
Leading suicide theories and research in adults suggest that pain can exacerbate the suicidal risk of an individual. Although pain and suicidality (including suicidal ideation, behaviour, and death by suicide) both increase in prevalence during adolescence, the relationship between these factors remains unclear. We aimed to systematically review the empirical evidence for such an association in adolescence. We included 25 observational studies published between January 1961 and December 2018, exploring the potential association between pain and suicidality in adolescents aged 10-19 years. Across various samples and manifestations of pain and suicidality, we found that pain approximately doubles the suicidal risk in adolescents, with a few studies suggesting that pain can predict suicidality longitudinally. Although depression was an important factor, it did not fully explain the association between pain and suicidality. Evidence for associations between pain characteristics and suicidality is sparse and inconclusive, and potentially hides developmental differences between adolescents and adults. Identification of psychological mediators and moderators is required to develop interventions tailored to the needs of adolescents experiencing pain. This study is registered with the PROSPERO database, number CRD42018097226.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.