SynthesisThe Journal of thoracic and cardiovascular surgery2020
Development of a risk score for early saphenous vein graft failure: An individual patient data meta-analysis.
Synthesis in The Journal of thoracic and cardiovascular surgery, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05129228 (Intraoperative Optical Coherence Tomography of the Saphenous Vein Conduit in Patients Undergoing Coronary Artery Bypass Surgery), which is not on this map. Cited by 24 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Intraoperative Optical Coherence Tomography of the Saphenous Vein Conduit in Patients Undergoing Coronary Artery Bypass Surgery
Who cites it
24 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Pooled it
- Efficacy of dual antiplatelet therapy for three months versus 12 months after coronary artery bypass grafting: multicentre, double blinded, randomised controlled trial.BMJ (Clinical research ed.) · 2026Trial
- Antiplatelet therapy after coronary artery bypass surgery: five year follow-up of randomised DACAB trial.BMJ (Clinical research ed.) · 2024Trial
- Bilateral versus single internal mammary artery use in patients with chronic kidney disease.General thoracic and cardiovascular surgery · 2026Article
- Impact of bilateral internal mammary artery grafting in patients with mildly decreased renal function.General thoracic and cardiovascular surgery · 2026Article
- HDL-Adjusted Inflammatory Ratios and Sequential Graft Configuration are Associated with Mid-Term Saphenous Vein Graft Occlusion in a Post-CABG Angiography Cohort.Journal of inflammation research · 2026Article
- The Effect of Smoking on the Activated Clotting Time and the Incidence of Complications in Noncardiac Arterial Procedures.Journal of endovascular therapy : an official journal of the International Society of Endovascular Specialists · 2025Article
- Review
- Ticagrelor combined with aspirin may improve patency of vein graft one year after off-pump coronary artery bypass grafting: a single-center, randomized double-blinded clinical controlled trial.Frontiers in cardiovascular medicine · 2025Article
- Intra-operative and post-operative management of conduits for coronary artery bypass grafting: a clinical consensus statement of the European Society of Cardiology Working Group on Cardiovascular Surgery and the European Association for Cardio-Thoracic Surgery Coronary Task Force.European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery · 2024Review
- External stenting for saphenous vein grafts reduces early postoperative graft failure.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Outcomes after surgical revascularization in diabetic patients.Interdisciplinary cardiovascular and thoracic surgery · 2024Article
- Angiographic Outcomes for Arterial and Venous Conduits Used in CABG.Journal of clinical medicine · 2023Review
- Secondary prevention is as important as surgical technique.Journal of cardiac surgery · 2022Article
- Angiographically Patent Saphenous Vein Graft to Left Anterior Descending Artery at 51 Years Post-Coronary Artery Bypass Grafting.CJC open · 2022Article
- Mercaptoalbumin Is Associated with Graft Patency in Patients Undergoing Coronary Artery Bypass Grafting.Antioxidants (Basel, Switzerland) · 2022Article
- Commentary: Ticagrelor monotherapy-Not for CABG?Journal of cardiac surgery · 2022Article
- Article
- The evolving evidence base for coronary artery bypass grafting and arterial grafting in 2021: How to improve vein graft patency.JTCVS techniques · 2021Article
- Observational
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectivesEarly saphenous vein graft (SVG) occlusion is typically attributed to technical factors. We aimed at exploring clinical, anatomical, and operative factors associated with the risk of early SVG occlusion (within 12 months postsurgery).
methodsPublished literature in MEDLINE was searched for studies reporting the incidence of early SVG occlusion. Individual patient data (IPD) on early SVG occlusion were used from the SAFINOUS-CABG Consortium. A derivation (n = 1492 patients) and validation (n = 372 patients) cohort were used for model training (with 10-fold cross-validation) and external validation respectively.
resultsIn aggregate data meta-analysis (48 studies, 41,530 SVGs) the pooled estimate for early SVG occlusion was 11%. The developed IPD model for early SVG occlusion, which included clinical, anatomical, and operative characteristics (age, sex, dyslipidemia, diabetes mellitus, smoking, serum creatinine, endoscopic vein harvesting, use of complex grafts, grafted target vessel, and number of SVGs), had good performance in the derivation (c-index = 0.744; 95% confidence interval [CI], 0.701-0.774) and validation cohort (c-index = 0.734; 95% CI, 0.659-0.809). Based on this model. we constructed a simplified 12-variable risk score system (SAFINOUS score) with good performance for early SVG occlusion (c-index = 0.700, 95% CI, 0.684-0.716).
conclusionsFrom a large international IPD collaboration, we developed a novel risk score to assess the individualized risk for early SVG occlusion. The SAFINOUS risk score could be used to identify patients that are more likely to benefit from aggressive treatment strategies.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.