ArticleMagnetic resonance in medicine2020
Calibration of arterial spin labeling data-potential pitfalls in post-processing.
Article in Magnetic resonance in medicine, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
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29 citing papers in PubMed.
- Endocrine modulation of cortical and retinal baseline perfusion across the menstrual cycle.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2026Article
- A parameterized gamma-variate function can describe the temporal response of cerebral blood flow after Acetazolamide injection in Moyamoya patients.Neuroimage. Reports · 2026Article
- Cerebrovascular Function in Women With Polycystic Ovary Syndrome: A Pilot Multi-Parameter Magnetic Resonance Imaging Study.Clinical endocrinology · 2026Article
- Combined angiography and perfusion using radial imaging and arterial spin labeling with structural contrast.Magnetic resonance in medicine · 2026Article
- Mapping cerebral blood perfusion and its links to multi-scale brain organization across the human lifespan.PLoS biology · 2025Article
- Regional changes in cerebral perfusion with age when accounting for changes in gray-matter volume.Magnetic resonance in medicine · 2025Article
- Stochastic variational inference improves quantification of multiple timepoint arterial spin labelling perfusion MRI.Frontiers in neuroscience · 2025Article
- Arterial spin labelling perfusion MRI analysis for the Human Connectome Project Lifespan Ageing and Development studies.Imaging neuroscience (Cambridge, Mass.) · 2025Article
- Recommendations for quantitative cerebral perfusion MRI using multi-timepoint arterial spin labeling: Acquisition, quantification, and clinical applications.Magnetic resonance in medicine · 2024Review
- The effect of post-labeling delay on cerebral blood flow is influenced by age and sex: a study based on arterial spin-labeling magnetic resonance imaging.Quantitative imaging in medicine and surgery · 2024Article
- Method for detection of cerebral blood flow in neurointensive care using longitudinal arterial spin labeling MRI.PloS one · 2024Article
- Article
- Specificity of Quantitative Functional Brain Mapping with Arterial Spin-Labeling for Preoperative Assessment.AJNR. American journal of neuroradiology · 2023Article
- Current state and guidance on arterial spin labeling perfusion MRI in clinical neuroimaging.Magnetic resonance in medicine · 2023Article
- Cortical oxygen extraction fraction using quantitative BOLD MRI and cerebral blood flow during vasodilation.Frontiers in physiology · 2023Article
- Modelling spatiotemporal dynamics of cerebral blood flow using multiple-timepoint arterial spin labelling MRI.Frontiers in physiology · 2023Article
- ASL MRI informs blood flow to chronic stroke lesions in patients with aphasia.Frontiers in physiology · 2023Article
- BASIL: A toolbox for perfusion quantification using arterial spin labelling.Imaging neuroscience (Cambridge, Mass.) · 2023Article
- Arterial Spin Labeling Perfusion in Pediatric Brain Tumors: A Review of Techniques, Quality Control, and Quantification.Cancers · 2022Review
- ASL-BIDS, the brain imaging data structure extension for arterial spin labeling.Scientific data · 2022Article
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8 authors.
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Abstract
purposeTo assess the impact of the different post-processing options in the calibration of arterial spin labeling (ASL) data on perfusion quantification and its reproducibility. THEORY AND
methodsAbsolute quantification of perfusion measurements is one of the promises of ASL techniques. However, it is highly dependent on a calibration procedure that involves a complex processing pipeline for which no standardized procedure has been fully established. In this work, we systematically compare the main ASL calibration methods as well as various post-processing calibration options, using 2 data sets acquired with the most common sequences, pulsed ASL and pseudo-continuous ASL.
resultsSignificant and sometimes large discrepancies in ASL perfusion quantification were obtained when using different post-processing calibration options. Nevertheless, when using a set of theoretically based and carefully chosen options, only small differences were observed for both reference tissue and voxelwise methods. The voxelwise and white matter reference tissue methods were less sensitive to post-processing options than the cerebrospinal fluid reference tissue method. However, white matter reference tissue calibration also produced poorer reproducibility results. Moreover, it may also not be an appropriate reference in case of white matter pathology.
conclusionPoor post-processing calibration options can lead to large errors in perfusion quantification, and a complete description of the calibration procedure should therefore be reported in ASL studies. Overall, our results further support the voxelwise calibration method proposed by the ASL white paper, particularly given the advantage of being relatively simple to implement and intrinsically correcting for the coil sensitivity profile.
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