ArticleJournal of the American Geriatrics Society2019
The Caregiver Burden of Delirium in Older Adults With Alzheimer Disease and Related Disorders.
Article in Journal of the American Geriatrics Society, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.
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Who cites it
12 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Medication Causes and Treatment of Delirium in Patients With and Without Dementia.Brain and behavior · 2025Pooled it
- Pooled it
- Dementia Caregivers' Preferences for Involvement in Delirium Care During Hospitalization.Journal of the American Geriatrics Society · 2026Article
- A Toolkit for Delirium Identification and Promoting Partnerships Between Carers and Nurses: A Pilot Pre-Post Feasibility Study.Journal of general internal medicine · 2024Observational
- The burden of traumatic brain injury on caregivers: exploring the predictive factors in a multi-centric study.BMC psychology · 2024Article
- Optimizing delirium care in the era of Age-Friendly Health System.Journal of the American Geriatrics Society · 2024Article
- One-year Medicare costs associated with delirium in older hospitalized patients with and without Alzheimer's disease dementia and related disorders.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2023Article
- Predictors of Caregiver Burden in Delirium: Patient and Caregiver Factors.Journal of gerontological nursing · 2021Article
- Does Alzheimer's Disease and Related Dementias Modify Delirium Severity and Hospital Outcomes?Journal of the American Geriatrics Society · 2020Article
- Longitudinal validation of an electronic health record delirium prediction model applied at admission in COVID-19 patients.General hospital psychiatryArticle
- Stratified delirium risk using prescription medication data in a state-wide cohort.General hospital psychiatryArticle
- Multidimensional burden of caregivers of Alzheimer's disease and related dementia in China: A nationwide cross-sectional study.Journal of Alzheimer's disease reportsArticle
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
objectivesTo measure the burden of delirium in older adults with or without Alzheimer disease or related disorders (ADRDs).
designProspective, observational cohort.
settingInpatient hospital and study participants' homes.
participantsA subset (n = 267) of older medical and surgical patients and their caregivers enrolled in the Better Assessment of Illness study. MEASUREMENTS: Delirium burden was measured using the DEL-B instrument (range = 0-40, with higher scores indicating greater burden) in caregivers (DEL-B-C) and patients 1 month after hospitalization. Severity of cognitive impairment (Montreal Cognitive Assessment [MoCA]), delirium presence (Confusion Assessment Method [CAM]), and delirium severity (CAM-Severity [CAM-S]) were measured during hospitalization and at 1-month follow-up. ADRD diagnosis was determined by a clinical consensus process.
resultsFor patients with (n = 56) and without (n = 211) ADRD, both DEL-B instruments had good internal consistency. DEL-B-C scores had a median (interquartile range) among caregivers of patients with and without ADRD of 9 (5-15) and 5 (1-11), respectively (P < .05). If the patient developed delirium, caregivers experienced greater burden (β[delirium × ADRD] = -.29; P = .42), regardless of ADRD status. Further, caregiver burden was modestly correlated with patient MoCA scores (Spearman correlation coefficient, ρ = -0.18; P = .01). Patients with ADRD who developed delirium self-reported less burden than those without ADRD (β[delirium × ADRD] = -.67; P = .044). As with caregivers, delirium burden was modestly correlated with patient MoCA score (ρ = -0.18; P = .005) and correlated with the CAM-S in patients without ADRD (ρ = 0.38; P < .001) but not for patients with ADRD (ρ = -0.07; P = .61).
conclusionsDelirium resulted in the same degree of increased caregiver burden regardless of whether a patient had ADRD, signifying delirium is equally stressful to caregivers, even among those with experience caring for someone with a chronic cognitive disorder. Delirium burden is only modestly associated with degree of cognitive impairment, suggesting that other aspects of delirium contribute to burden. J Am Geriatr Soc 67:2587-2592, 2019.
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