Evidence map›Paper›PMID 31605278›Full record

Trial reportDigestive diseases and sciences2020

Risk Factors Associated with Inadequate Bowel Preparation in Patients with Functional Constipation.

Xiaoyang Guo, Xin Shi, Xiaoyu Kang, Hui Luo, Xiangping Wang, Hui Jia, Qin Tao, Jingjie Wang, Mingxin Zhang, Jinhai Wang and 7 more

Registry-linked trialAbstract readClinical TrialMulticenter Study
PubMed Publisher
In one paragraph

Trial report in Digestive diseases and sciences, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT02842411 (Risk Factors for Inadequate Bowel Preparation in Patients With Chronic Constipation), which is not on this map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02842411 unknown statusnot on this map

Risk Factors for Inadequate Bowel Preparation in Patients With Chronic Constipation

TypeobservationalSponsorAir Force Military Medical University, ChinaRan2016 to 2017Enrolled200ConditionsConstipation
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 27 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. An abdominal vibration combined with walking exercise (AVCWE) program for older patients with constipation: Development and feasibility study.Saudi journal of gastroenterology : official journal of the Saudi Gastroenterology Association · 2024
    Article
  6. Article
  7. Article
  8. Current Applications of Fecal Microbiota Transplantation in Functional Constipation.Evidence-based complementary and alternative medicine : eCAM · 2022
    Review
  9. Review
  10. Article
  11. Review
  12. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors at 4 institutions in 1 country.

Xiaoyang GuoState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China.
Xin ShiState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China.
Xiaoyu KangState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China.
Hui LuoState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China.
Xiangping WangState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China.
Hui JiaState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China.
Qin TaoState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China.
Jingjie WangDepartment of Gastroenterology, Tangdu Hospital, Fourth Military Medical University, Xi'an, China.
Mingxin ZhangDepartment of Gastroenterology, The First Affiliated Hospital of Xi'an Medical University, Xi'an, China.
Jinhai WangDepartment of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Xiaolan LuDepartment of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Shiyang MaDepartment of Gastroenterology, The Second Affiliated Hospital of Xi'an Jiaotong University, Xi'an, China.
Tao LinDepartment of Gastroenterology, The 451 Hospital of PLA, Xi'an, China.
Yujie JingDepartment of Gastroenterology, The 451 Hospital of PLA, Xi'an, China.
Yanglin PanState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China. yanglinpan@hotmail.com.ORCID 0000-0002-7183-6716
Xuegang GuoState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China.
Daiming FanState Key Laboratory of Cancer Biology, National Clinical Research Center for Digestive Diseases and Xijing Hospital of Digestive Diseases, Fourth Military Medical University, 127 Changle West Road, Xi'an, 710032, Shaanxi, China.
National Clinical Research Center for Digestive Diseases · CNSecond Affiliated Hospital of Xi'an Jiaotong University · CNPeople 's Liberation Army 451 Hospital · CNXi'an Medical University · CN

Funding

National Key Technology R&D Program 2015BAI13B07National Natural Science Foundation of China 81370585
6 · The paper itself

Abstract

backgroundConstipation is a common reason of poor bowel preparation, which negatively influences the quality of colonoscopy. Risk factors for inadequate bowel preparation in constipated patients remain unclear.

aimsThis study aimed to investigate the high-risk factors that might influence the quality of bowel preparation in patients with functional constipation.

methodsConsecutive patients with functional constipation who underwent colonoscopy between June 2016 and April 2017 were enrolled. A standard split dose of 4 l polyethylene glycol was used for bowel preparation. Patient- and procedure-related parameters were recorded. The primary outcome was an adequate rate of bowel preparation. Risk factors for inadequate bowel preparation were screened by multivariate logistic regression analysis.

resultsA total of 199 patients were included. Adequate bowel preparation was found in 62.8% (125/199) of patients. At multivariate analysis, Bristol stool form scale (BSFS) 1 [odds ratio (OR) 2.73, 95% confidence interval (CI) 1.26-5.90; P = 0.011], rectal pain score during defecation < 2 (OR 4.14, 95% CI 1.22-13.97; P = 0.022), and starting-to-defecation interval ≥ 4 h (OR 3.83, 95% CI 1.34-10.91; P = 0.012) were risk factors for inadequate bowel preparation in patients with constipation. For patients with no, 1, 2, or 3 risk factors, the rates of inadequate bowel preparation were 11%, 23%, 49%, and 65%, respectively.

conclusionsWith the standard preparation regime, > 1/3 of patients with functional constipation had inadequate bowel cleansing. BSFS 1, rectal pain score during defecation < 2, and starting-to-defecation interval ≥ 4 h were identified as independent risk factors for inadequate bowel preparation in constipated patients.

trial registrationClinicalTrials.gov number NCT02842411.

Indexed as

AdultCatharticsColonoscopyConstipationDefecationFemaleHumansMaleMiddle AgedPolyethylene GlycolsProspective StudiesRisk FactorsCatharticsPolyethylene GlycolsBowel preparationColonoscopyFunctional constipationRisk factor

Identifiers

PMID31605278
OpenAlexW2979774980

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.