Evidence map›Paper›PMID 31605244›Full record

ArticleMikrochimica acta2019

Amperometric immunoassay for the carcinoembryonic antigen by using a peroxidase mimic consisting of palladium nanospheres functionalized with glutathione-capped gold nanoparticles on graphene oxide.

Zhaoling Tan, Linlin Cao, Yuying Yang, Qin Yan, Qing Liu, Wen Zhang, Pingping Zhao, Yueyun Li, Daopeng Zhang

Abstract read
PubMed Publisher
In one paragraph

Article in Mikrochimica acta, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Zhaoling TanSchool of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, 255049, People's Republic of China.
Linlin CaoDepartment of Clinical Laboratory, Zibo Central Hospital, Zibo, 255036, People's Republic of China.
Yuying YangSchool of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, 255049, People's Republic of China.
Qin YanSchool of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, 255049, People's Republic of China.
Qing LiuSchool of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, 255049, People's Republic of China. qingliu0315@163.com.
Wen ZhangDepartment of Clinical Laboratory, Zibo Central Hospital, Zibo, 255036, People's Republic of China.
Pingping ZhaoCollege of Chemical and Environmental Engineering, Shandong University of Science and Technology, Qingdao, 266510, People's Republic of China.
Yueyun LiSchool of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, 255049, People's Republic of China.
Daopeng ZhangSchool of Chemistry and Chemical Engineering, Shandong University of Technology, Zibo, 255049, People's Republic of China.
Shandong University of Technology · CNCentral Hospital of Zibo · CNShandong University of Science and Technology · CN

Funding

the National Natural Science Foundation of China 21405095; 21575079; 21671121the Shandong Provincial Natural Science Foundation ZR2018MB008, ZR2018MB012
6 · The paper itself

Abstract

A composite nanoenzyme was used in a sandwich-type electrochemical immunoassay for the carcinoembryonic antigen (CEA). Hierarchically porous palladium nanospheres (Pd NPs) were functionalized with glutathione-capped gold nanoparticles (G-Au NPs) and then loaded onto graphene oxide (GO) to obtain a peroxidase mimicking nanoenzyme of type GO-supported G-Au/Pd. The composite can catalyze the oxidation of the substrate tetramethylbenzidine (TMB) by H

Indexed as

Antibodies, ImmobilizedBenzidinesBiomarkers, TumorBiomimetic MaterialsCarcinoembryonic AntigenColoring AgentsElectrochemical TechniquesGlutathioneGoldGraphiteHumansHydrogen PeroxideImmunoassayLimit of DetectionMetal NanoparticlesNanospheres3,3',5,5'-tetramethylbenzidineAntibodies, ImmobilizedBenzidinesBiomarkers, TumorCarcinoembryonic AntigenColoring AgentsGlutathioneGoldgraphene oxideGraphiteHydrogen PeroxidePalladiumPeroxidaseCEAGO supported G-Au/PdNanoenzymesSandwich-type electrochemical immunosensorSignal amplification

Identifiers

PMID31605244
OpenAlexW2980076271

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.