Evidence map›Paper›PMID 31604998›Full record

ArticleScientific reports2019

Kawasaki Disease following administration of 13-valent pneumococcal conjugate vaccine in young children.

Chee Fu Yung, Xiangmei Ma, Yin Bun Cheung, Bee Khiam Oh, Sally Soh, Koh Cheng Thoon

Erratum issuedOpen access · goldAbstract read
In one paragraph

Article in Scientific reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Chee Fu YungInfectious Disease Service, KK Women's and Children's Hospital, 100 Bukit Timah Road, 229899, Singapore, Singapore. Yung.Chee.Fu@singhealth.com.sg.
Xiangmei MaCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Yin Bun CheungCentre for Quantitative Medicine, Duke-NUS Medical School, Singapore, Singapore.
Bee Khiam OhInfectious Disease Service, KK Women's and Children's Hospital, 100 Bukit Timah Road, 229899, Singapore, Singapore.
Sally SohVigilance Branch, Health Products Regulation Group, Health Sciences Authority, Singapore, Singapore.
Koh Cheng ThoonInfectious Disease Service, KK Women's and Children's Hospital, 100 Bukit Timah Road, 229899, Singapore, Singapore.
KK Women's and Children's Hospital · SGDuke-NUS Medical School · SGHealth Sciences Authority · SGSingHealth · SGTampere University Hospital · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Kawasaki disease (KD) is a systemic vasculitis mainly affecting young children and the leading cause of acquired heart disease in developed countries. We performed a self-controlled case series analysis to investigate the association between PCV13 and KD. All hospitalized KD cases <2 y old from our hospital in Singapore from 2010 to 2014 were included. Complete KD cases were classified based on the definitions of the American Heart Association. During the study period, 288 KD cases were identified. A total of 21 KD cases (12 were classified as Complete KD) had date of onset within the risk interval of day 1 to day 28 post PCV13. The age-adjusted Relative Incidence (RI) for KD following PCV13 dose 1, dose 2 and dose 3 were 1.40 (95%CI, 0.72 to 2.71), 1.23 (95% CI, 0.62 to 2.44) and 0.34 (95% CI, 0.08 to 1.40) respectively. There were seven Complete KD cases with onset during the risk interval after dose 1 of PCV13 (age-adjusted RI 2.59, 95%confidence interval (CI), 1.16 to 5.81). We did not detect a significant increased risk for overall KD among PCV13 recipients. However, a significant association between PCV13 and Complete KD was noted following receipt of the first dose of PCV13.

Indexed as

FemaleHumansImmunization ScheduleIncidenceInfantMaleMucocutaneous Lymph Node SyndromePneumococcal InfectionsPneumococcal VaccinesRisk FactorsSingaporeStreptococcus pneumoniaeVaccinationVaccines, Conjugate13-valent pneumococcal vaccinePneumococcal VaccinesVaccines, Conjugate

Identifiers

PMID31604998
PMCPMC6788987
OpenAlexW2980121978

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.