Evidence map›Paper›PMID 31604797›Full record

ArticleGenetics2019

Histone Chaperone Paralogs Have Redundant, Cooperative, and Divergent Functions in Yeast.

Neda Savic, Shawn P Shortill, Misha Bilenky, Joseph M Dobbs, David Dilworth, Martin Hirst, Christopher J Nelson

Open access · bronzeAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Genetics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 43% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Neda SavicDepartment Biochemistry and Microbiology, University of Victoria, BC V8W 3P6, Canada.
Shawn P ShortillDepartment Biochemistry and Microbiology, University of Victoria, BC V8W 3P6, Canada.ORCID 0000-0001-8742-7442
Misha BilenkyBC Cancer Agency Genome Sciences Centre and the Department of Microbiology & Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Joseph M DobbsDepartment Biochemistry and Microbiology, University of Victoria, BC V8W 3P6, Canada.ORCID 0000-0002-4123-2209
David DilworthDepartment Biochemistry and Microbiology, University of Victoria, BC V8W 3P6, Canada.
Martin HirstBC Cancer Agency Genome Sciences Centre and the Department of Microbiology & Immunology, Michael Smith Laboratories, University of British Columbia, Vancouver, BC V6T 1Z3, Canada.
Christopher J NelsonDepartment Biochemistry and Microbiology, University of Victoria, BC V8W 3P6, Canada cjn@uvic.ca.
University of Victoria · CACanada's Michael Smith Genome Sciences Centre · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gene duplications increase organismal robustness by providing freedom for gene divergence or by increasing gene dosage. The yeast histone chaperones Fpr3 and Fpr4 are paralogs that can assemble nucleosomes

Indexed as

Sequence Homology, Amino AcidChromatinDNA, Ribosomal SpacerEpistasis, GeneticExosomesGenes, SuppressorGenomic InstabilityHistone ChaperonesImmunophilinsSaccharomyces cerevisiaeSaccharomyces cerevisiae ProteinsTacrolimus Binding ProteinsTranscription, GeneticTranscriptomeChromatinDNA, Ribosomal SpacerFPR3 protein, S cerevisiaeFpr4 protein, S cerevisiaeHistone ChaperonesImmunophilinsSaccharomyces cerevisiae ProteinsTacrolimus Binding Proteinschromatingenetic interactionshistone chaperonenucleolusparalog

Identifiers

PMID31604797
PMCPMC6893378
OpenAlexW2980275135

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.