Evidence map›Paper›PMID 31604715›Full record

ArticleBMJ case reports2019

Clinical approach to the diagnosis and successful management of anti-NMDA receptor encephalitis when antibody testing is not possible.

Anil Frank Ramlackhansingh, Alexi Christopher King, Shamera Maharaj, David Joseph King

Open access · greenAbstract readCase Reports
In one paragraph

Article in BMJ case reports, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 37% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Anil Frank RamlackhansinghDepartment of Adult Medicine, University of the West Indies at Saint Augustine Faculty of Medical Sciences, Saint Augustine, Trinidad and Tobago.
Alexi Christopher KingMedicine, Port of Spain General Hospital, Port of Spain, Trinidad and Tobago.
Shamera MaharajInternal Medicine, Port of Spain General Hospital, Port of Spain, Trinidad and Tobago.
David Joseph KingDepartment of Internal Medicine, North West Regional Health Authority, Port of Spain, Trinidad and Tobago.
Port of Spain General Hospital · TTUniversity of the West Indies · TT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Anti-N-methyl-D-aspartate (NMDA) receptor encephalitis is a multistage illness that progresses from psychosis, memory deficits, seizures and language disintegration to a state of unresponsiveness with catatonic features often associated with abnormal movements, and autonomic and breathing instability. While the disorder predominantly affects children and young adults, and occurs with or without tumour association, the presence of a tumour (usually an ovarian teratoma) is dependent on the age, sex and ethnicity.Teratomas present more frequently in women older than 18 years, and are more predominant in black women than Caucasians. Here we present the case of a patient with probable anti-NMDA receptor encephalitis. She was subsequently found to have a mature teratoma of the ovary (dermoid cyst). Despite immune-modulated therapy, surgery was eventually performed to remove the cyst. This was met with a good clinical recovery.

Indexed as

AdultAnti-N-Methyl-D-Aspartate Receptor EncephalitisDiagnosis, DifferentialElectroencephalographyFemaleHumansMagnetic Resonance ImagingOvarian NeoplasmsTeratomaTomography, X-Ray ComputedYoung Adultepilepsy and seizuresgynecological cancer

Identifiers

PMID31604715
PMCPMC6803151
OpenAlexW2979649559

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.