Evidence map›Paper›PMID 31604547›Full record

ReviewHandbook of clinical neurology2019

Central taste anatomy and physiology.

Roberto Vincis, Alfredo Fontanini

Abstract readReview
In one paragraph

Review in Handbook of clinical neurology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 45 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
45citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

45 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Review
  5. Review
  6. Variations in basic taste perception and body mass index.Journal of diabetes and metabolic disorders · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Cortical Coding of Gustatory and Thermal Signals in Active Licking Mice.bioRxiv : the preprint server for biology · 2024
    Article
  15. Article
  16. Neuronal Activity in the Gustatory Cortex during Economic Choice.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Article
  17. Article
  18. Unique Properties of Thalamocortical Projections to the Gustatory Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024
    Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Roberto VincisDepartment of Biological Science and Program in Neuroscience, Florida State University, Tallahassee, FL, United States. Electronic address: rvincis@fsu.edu.
Alfredo FontaniniDepartment of Neurobiology and Behavior, State University of New York at Stony Brook, Stony Brook, NY, United States. Electronic address: alfredo.fontanini@stonybrook.edu.

Funding

Synaptic organization and plasticity of the input from the basolateral amygdala tR01DC013770 · NIDCD · STATE UNIVERSITY NEW YORK STONY BROOK · PI Alfredo Fontanini, Arianna Maffei · 2014 to 2026
$4.6M
Effects of expectation on gustatory cortical activityR01DC010389 · NIDCD · STATE UNIVERSITY NEW YORK STONY BROOK · PI FONTANINI, ALFREDO · 2009 to 2014
$2.0M
Laminar differences in taste coding: a circuit perspectiveR01DC015234 · NIDCD · STATE UNIVERSITY NEW YORK STONY BROOK · PI FONTANINI, ALFREDO, MAFFEI, ARIANNA · 2016 to 2020
$2.0M
The synaptic basis of cortical taste processingR01DC012543 · NIDCD · STATE UNIVERSITY NEW YORK STONY BROOK · PI FONTANINI, ALFREDO · 2012 to 2016
$1.6M
The role of mediodorsal thalamus in tasteR21DC016714 · NIDCD · STATE UNIVERSITY NEW YORK STONY BROOK · PI VINCIS, ROBERTO · 2018 to 2020
$465k
NIDCD NIH HHS R01 DC010389NIDCD NIH HHS R01 DC012543NIDCD NIH HHS R01 DC013770NIDCD NIH HHS R01 DC015234NIDCD NIH HHS R21 DC016714
6 · The paper itself

Abstract

The gustatory system contributes to the flavor of foods and beverages and communicates information about nutrients and poisons. This system has evolved to detect and ultimately respond to hydrophilic molecules dissolved in saliva. Taste receptor cells, located in taste buds and distributed throughout the oral cavity, activate nerve afferents that project to the brainstem. From here, information propagates to thalamic, subcortical, and cortical areas, where it is integrated with information from other sensory systems and with homeostatic, visceral, and affective processes. There is considerable divergence, as well as convergence, of information between multiple regions of the central nervous system that interact with the taste pathways, with reciprocal connections occurring between the involved regions. These widespread interactions among multiple systems are crucial for the perception of food. For example, memory, hunger, satiety, and visceral changes can directly affect and can be affected by the experience of tasting. In this chapter, we review the literature on the central processing of taste with a specific focus on the anatomic and physiologic responses of single neurons. Emphasis is placed on how information is distributed along multiple systems with the goal of better understanding how the rich and complex sensations associated with flavor emerge from large-scale, systems-wide, interactions.

Indexed as

Afferent PathwaysAnimalsBrainHumansNerve NetNeuronsTasteThalamusBrainstemCortexCross-modalExpectationGustatoryHedonic valueLimbic systemRewardTasteThalamus

Identifiers

PMID31604547
PMCPMC6989094

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.