Evidence map›Paper›PMID 31604468›Full record

ArticleBMC cancer2019

Depression and anxiety among people living with and beyond cancer: a growing clinical and research priority.

Claire L Niedzwiedz, Lee Knifton, Kathryn A Robb, Srinivasa Vittal Katikireddi, Daniel J Smith

Registry-linked trialAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in BMC cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07167056 (Artificial Intelligence-Powered Support For Quality Of Life Improvement In Patients With Cancer), which is not on this map. Cited by 361 papers, 21 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
361citing papers in PubMed, 21 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07167056 narecruitingnot on this mapstarted 2025, after this paper: background citation

Artificial Intelligence-Powered Support For Quality Of Life Improvement In Patients With Cancer

TypeinterventionalSponsorCase Comprehensive Cancer CenterRan2025 to 2027Enrolled60ConditionsCancerArmsStandard of Care Psychotherapy, WYSA App
3 · Its place in the literature

Who cites it

361 citing papers in PubMed, 21 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Digital and AI-enhanced psychosocial interventions in breast cancer patients: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
    Pooled it
  5. Pooled it
  6. Pooled it
  7. Pooled it
  8. Pooled it
  9. Pooled it
  10. Pooled it
  11. Pooled it
  12. Pooled it
  13. Pooled it
  14. Pooled it
  15. Pooled it
  16. Effectiveness of creative arts therapy for adult patients with cancer: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it
  17. Pooled it
  18. Pooled it
  19. Pooled it
  20. Effectiveness of dance movement therapy and dance movement interventions on cancer patients' health-related outcomes: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2024
    Pooled it

301 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Claire L NiedzwiedzInstitute of Health & Wellbeing, University of Glasgow, Glasgow, Scotland, UK. claire.niedzwiedz@glasgow.ac.uk.ORCID http://orcid.org/0000-0001-6133-4168
Lee KniftonUniversity of Strathclyde, Centre for Health Policy, Glasgow, Scotland, UK.
Kathryn A RobbInstitute of Health & Wellbeing, University of Glasgow, Glasgow, Scotland, UK.
Srinivasa Vittal KatikireddiMRC/CSO Social and Public Health Sciences Unit, University of Glasgow, Glasgow, Scotland, UK.
Daniel J SmithInstitute of Health & Wellbeing, University of Glasgow, Glasgow, Scotland, UK.

Funding

Chief Scientist Office SCAF/15/02Medical Research Council MC_UU_12017/13Medical Research Council MC_UU_12017/15Medical Research Council MR/R024774/1NRS Senior Clinical Fellowship SCAF/15/02Scottish Government Chief Scientist Office SPHSU13Scottish Government Chief Scientist Office SPHSU15
6 · The paper itself

Abstract

backgroundA cancer diagnosis can have a substantial impact on mental health and wellbeing. Depression and anxiety may hinder cancer treatment and recovery, as well as quality of life and survival. We argue that more research is needed to prevent and treat co-morbid depression and anxiety among people with cancer and that it requires greater clinical priority. For background and to support our argument, we synthesise existing systematic reviews relating to cancer and common mental disorders, focusing on depression and anxiety. We searched several electronic databases for relevant reviews on cancer, depression and anxiety from 2012 to 2019. Several areas are covered: factors that may contribute to the development of common mental disorders among people with cancer; the prevalence of depression and anxiety; and potential care and treatment options. We also make several recommendations for future research. Numerous individual, psychological, social and contextual factors potentially contribute to the development of depression and anxiety among people with cancer, as well as characteristics related to the cancer and treatment received. Compared to the general population, the prevalence of depression and anxiety is often found to be higher among people with cancer, but estimates vary due to several factors, such as the treatment setting, type of cancer and time since diagnosis. Overall, there are a lack of high-quality studies into the mental health of people with cancer following treatment and among long-term survivors, particularly for the less prevalent cancer types and younger people. Studies that focus on prevention are minimal and research covering low- and middle-income populations is limited.

conclusionResearch is urgently needed into the possible impacts of long-term and late effects of cancer treatment on mental health and how these may be prevented, as increasing numbers of people live with and beyond cancer.

Indexed as

ResearchAdaptation, PsychologicalAdolescentAdultAgedAged, 80 and overAnxietyCancer SurvivorsCognitive Behavioral TherapyDepressionFemaleHumansMaleMental HealthMeta-Analysis as TopicNeoplasmsAnxietyCancerDepressionMental healthMultimorbidityOncologyPsychiatrySurvivorship

Identifiers

PMID31604468
PMCPMC6788022

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.