Evidence map›Paper›PMID 31604006›Full record

ArticleAngewandte Chemie (International ed. in English)2019

Accessing 1,2-Substituted Cyclobutanes through 1,2-Azaborine Photoisomerization.

Zachary X Giustra, Xinyu Yang, Min Chen, Holger F Bettinger, Shih-Yuan Liu

Abstract read
In one paragraph

Article in Angewandte Chemie (International ed. in English), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. A Catalyst-Controlled Divergent Rearomatization of BN-Benzvalene.Journal of the American Chemical Society · 2026
    Article
  2. Article
  3. Positional Isomerization of 1,2-Azaborine through BN-Benzvalene.Journal of the American Chemical Society · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. A Nitrilium-TypeJournal of the American Chemical Society · 2025
    Article
  9. Article
  10. Boron-Nitrogen-Containing Benzene Valence Isomers.Chemistry (Weinheim an der Bergstrasse, Germany) · 2024
    Article
  11. A BN-Benzvalene.Journal of the American Chemical Society · 2024
    Article
  12. Borylated cyclobutanesChemical science · 2024
    Article
  13. Article
  14. Article
  15. Article
  16. Photosensitized [2+2]-Cycloadditions of Alkenylboronates and Alkenes.Angewandte Chemie (International ed. in English) · 2022
    Article
  17. Review
  18. The Versatile Reaction Chemistry of an Alpha-Boryl Diazo Compound.Journal of the American Chemical Society · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Zachary X GiustraDepartment of Chemistry, Boston College, Chestnut Hill, MA, 02467-3860, USA.
Xinyu YangDepartment of Chemistry, Boston College, Chestnut Hill, MA, 02467-3860, USA.
Min ChenDepartment of Chemistry, Boston College, Chestnut Hill, MA, 02467-3860, USA.
Holger F BettingerInstitut für Organische Chemie, Universität Tübingen, Auf der Morgenstelle 18, 72076, Tübingen, Germany.
Shih-Yuan LiuDepartment of Chemistry, Boston College, Chestnut Hill, MA, 02467-3860, USA.ORCID 0000-0003-3148-9147

Funding

Development of BN Heterocycles for Biomedical ResearchR01GM094541 · NIGMS · UNIVERSITY OF OREGON · PI LIU, SHIH-YUAN · 2010 to 2019
$2.8M
NIGMS NIH HHS R01 GM094541
6 · The paper itself

Abstract

We provide a seminal example of the utility of the 1,2-azaborine motif as a 4C+1N+1B synthon in organic synthesis. Specifically, conditions for the practically scalable photoisomerization of 1,2-azaborine in a flow reactor are reported that furnish aminoborylated cyclobutane derivatives. The C-B bonds could also be functionalized to furnish a diverse set of highly substituted cyclobutanes.

Indexed as

Aza CompoundsBoron CompoundsCyclobutanes1,2-azaborineAza CompoundsBoron CompoundsCyclobutanesboron-nitrogen heterocyclesflow chemistryphotochemistrysmall ring systemsvalence isomerization

Identifiers

PMID31604006
PMCPMC6917847

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.