Evidence map›Paper›PMID 31603758›Full record

ArticleJournal of studies on alcohol and drugs2019

Correlates and Potential Confounds of Cannabis Withdrawal Among High-Risk Adolescents.

Jarrod M Ellingson, L Cinnamon Bidwell, Christian J Hopfer, Kent E Hutchison, Angela D Bryan

Abstract read
PubMed Full text at PMC
In one paragraph

Article in Journal of studies on alcohol and drugs, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Jarrod M EllingsonDepartment of Psychology and Neuroscience, University of Colorado Boulder, Boulder, Colorado.
L Cinnamon BidwellDepartment of Psychology and Neuroscience, University of Colorado Boulder, Boulder, Colorado.
Christian J HopferDivision of Substance Dependence, Department of Psychiatry, University of Colorado School of Medicine, Aurora, Colorado.
Kent E HutchisonDepartment of Psychology and Neuroscience, University of Colorado Boulder, Boulder, Colorado.
Angela D BryanDepartment of Psychology and Neuroscience, University of Colorado Boulder, Boulder, Colorado.

Funding

The Effects of Cannabis Legalization and Persistent Use: A Longitudinal Study of Two Twin CohortsR01DA042755 · NIDA · UNIVERSITY OF COLORADO DENVER · PI Jarrod Martin Ellingson, SOO H RHEE · 2017 to 2026
$9.9M
Genetics and Progression of Early-onset Substance Dependence and HIV RiskR01DA035804 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HOPFER, CHRISTIAN J, STALLINGS, MICHAEL CRAIG · 2014 to 2018
$4.9M
Alcohol Use and HIV Risk: An InterventionR01AA013844 · NIAAA · UNIVERSITY OF NEW MEXICO · PI BRYAN, ANGELA · 2002 to 2013
$4.4M
Dismantling MBRP: Identifying Critical Neuroimmune Mechanisms of ActionR01AA024632 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI HUTCHISON, KENT E. · 2016 to 2020
$3.0M
Marijuana Harm Reduction: Innovative Strategies for Developing New KnowledgeR01DA039707 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HUTCHISON, KENT E. · 2016 to 2020
$2.2M
Mentoring Clinical Investigators in Adolescent-onset Substance Use Disorders ResearchK24DA032555 · NIDA · UNIVERSITY OF COLORADO DENVER · PI HOPFER, CHRISTIAN J · 2013 to 2022
$1.9M
Common mechanisms of the microbiota-gut-brain axis in alcohol use disorder and depression: A genetically informed investigationK23AA026635 · NIAAA · UNIVERSITY OF COLORADO DENVER · PI ELLINGSON, JARROD MARTIN · 2018 to 2022
$907k
Deconstructing the Smoking and ADHD Comorbidity: A Multilevel Genetic ApproachK23DA033302 · NIDA · UNIVERSITY OF COLORADO · PI BIDWELL, L. CINNAMON · 2012 to 2016
$871k
NIAAA NIH HHS K23 AA026635NIAAA NIH HHS R01 AA013844NIAAA NIH HHS R01 AA024632NIDA NIH HHS K23 DA033302NIDA NIH HHS K24 DA032555NIDA NIH HHS R01 DA035804NIDA NIH HHS R01 DA039707NIDA NIH HHS R01 DA042755
6 · The paper itself

Abstract

objectiveThe current study used a sample of high-risk adolescents to examine cannabis withdrawal correlates, including assessments of other drug withdrawal and affective lability that may confound cannabis withdrawal measurement.

methodA total of 448 high-risk adolescents, living in the Southwest United States, were recruited from a juvenile detention center for a sexual risk-reduction intervention study (60% male; 67% Hispanic). Assessments were administered every 3 months for a year, resulting in five assessments of drug use and withdrawal (cannabis, alcohol, nicotine). Affective lability was also assessed.

resultsForty-two percent of participants endorsed cannabis withdrawal at baseline. Participants used cannabis, on average, 3.3 days/week at baseline and 0.8-1.1 days/week at follow-ups. Cannabis use and withdrawal were only weakly to moderately correlated (r = .14-.32). Unexpectedly, alcohol withdrawal demonstrated strong correlations with cannabis withdrawal at all assessments (r = .41-.55). Furthermore, affective lability measures were related to cannabis withdrawal (r = .22-.32) but not with cannabis use (r = -.03-.09).

conclusionsWhereas cannabis withdrawal was only weakly to moderately related to cannabis use, it demonstrated strong associations with alcohol withdrawal across all assessments. In addition, affective lability measures were moderately correlated with cannabis withdrawal but not with cannabis use. Thus, other drug withdrawal and individual differences are essential to consider when assessing cannabis withdrawal.

Indexed as

AdolescentFemaleHumansMaleMarijuana AbuseSexual BehaviorSubstance-Related DisordersSubstance Withdrawal Syndrome

Identifiers

PMID31603758
PMCPMC6811723

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.