Evidence map›Paper›PMID 31603630›Full record

ArticleObesity (Silver Spring, Md.)2019

Antiobesity Medication Use in 2.2 Million Adults Across Eight Large Health Care Organizations: 2009-2015.

David R Saxon, Sean J Iwamoto, Christie J Mettenbrink, Emily McCormick, David Arterburn, Matthew F Daley, Caryn E Oshiro, Corinna Koebnick, Michael Horberg, Deborah R Young and 1 more

Abstract readHistorical Article
In one paragraph

Article in Obesity (Silver Spring, Md.), 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 79 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
79citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

79 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Clinical outcomes associated with anti-obesity medications in real-world practice: A systematic literature review.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2021
    Pooled it
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  17. Patients experience with preoperative use of anti-obesity medications and associations with bariatric surgery expectations.Surgery for obesity and related diseases : official journal of the American Society for Bariatric Surgery · 2025
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19 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

11 authors.

David R SaxonDivision of Endocrinology, Metabolism and Diabetes, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0002-4309-855X
Sean J IwamotoDivision of Endocrinology, Metabolism and Diabetes, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.ORCID 0000-0002-7316-8256
Christie J MettenbrinkDenver Health Medical Center, Denver, Colorado, USA.
Emily McCormickDenver Health Medical Center, Denver, Colorado, USA.
David ArterburnKaiser Permanente Washington Health Research Institute, Seattle, Washington, USA.
Matthew F DaleyKaiser Permanente Colorado Institute for Health Research, Denver, Colorado, USA.
Caryn E OshiroKaiser Permanente Center for Health Research Hawaii, Honolulu, Hawaii, USA.
Corinna KoebnickDepartment of Research and Evaluation, Kaiser Permanente, Pasadena, California, USA.
Michael HorbergKaiser Permanente Mid-Atlantic Permanente Research Institute, Rockville, Maryland, USA.
Deborah R YoungKaiser Permanente Mid-Atlantic Permanente Research Institute, Rockville, Maryland, USA.ORCID 0000-0002-8335-7851
Daniel H BessesenDivision of Endocrinology, Metabolism and Diabetes, University of Colorado, Anschutz Medical Campus, Aurora, Colorado, USA.

Funding

NIH Prior Approval Process ProfessionalUL1TR002535 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2018 to 2022
$51.1M
Colorado Clinical and Translational Sciences InstituteUL1TR001082 · NCATS · UNIVERSITY OF COLORADO DENVER · PI SOKOL, RONALD J. · 2013 to 2017
$48.0M
PILOT STUDY--SUBSTRATE METABOLISM IN EXTREMELY LOW BIRTH WEIGHT INFANTSP30DK048520 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI Wendy M Kohrt · 1995 to 2026
$32.6M
TRAINING PROGRAM IN DIABETES, ENDOCRINOLOGY &METABOLISMT32DK007446 · NIDDK · UNIVERSITY OF COLORADO DENVER · PI BESSESEN, DANIEL HOLLAND · 1986 to 2017
$5.6M
NCATS NIH HHS UL1 TR001082NCATS NIH HHS UL1 TR002535NIDDK NIH HHS P30 DK048520NIDDK NIH HHS T32 DK007446Patient-Centered Outcomes Research Institute CDRN-1306-04681
6 · The paper itself

Abstract

objectiveThe aim of this study was to examine the prescribing patterns and use of antiobesity medications in a large cohort of patients using data from electronic health records.

methodsPharmacy- and patient-level electronic health record data were obtained on 2,248,407 adults eligible for weight-loss medications from eight geographically dispersed health care organizations.

resultsA total of 29,964 patients (1.3% of total cohort) filled at least one weight-loss medication prescription. This cohort was 82.3% female, with median age 44.9 years and median BMI 37.2 kg/m

conclusionsWeight-loss medications are rarely prescribed to eligible patients. Phentermine accounted for > 75% of all medication days, with a majority of patients filling it for more than 4 months. Less than one-quarter of prescribing providers accounted for approximately 90% of all prescriptions.

Indexed as

AdultAnti-Obesity AgentsCohort StudiesDelivery of Health CareFemaleHistory, 21st CenturyHumansMaleObesityWeight LossAnti-Obesity Agents

Identifiers

PMID31603630
PMCPMC6868321

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.